CRCGN016_MCF10A.TP53.M_24H:K12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description wortmannin 1.11 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

401 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:K12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MCOLN1 mucolipin 1 6.50434
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 5.99486
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 5.78856
GPER1 G protein-coupled estrogen receptor 1 5.6477
STAP2 signal transducing adaptor family member 2 4.89439
STK10 serine/threonine kinase 10 4.6454
CXCL2 chemokine (C-X-C motif) ligand 2 4.47662
WIF1 WNT inhibitory factor 1 4.37009
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.88356
CRELD2 cysteine-rich with EGF-like domains 2 3.81468
SPAG4 sperm associated antigen 4 3.61928
TBX2 T-box 2 3.55973
CCP110 centriolar coiled coil protein 110kDa 3.37413
SCCPDH saccharopine dehydrogenase (putative) 3.20755
CDCA4 cell division cycle associated 4 3.14965
RHOBTB2 Rho-related BTB domain containing 2 3.13137
CADM1 cell adhesion molecule 1 3.13041
MUC2 mucin 2, oligomeric mucus/gel-forming 3.0406
GUCA2A guanylate cyclase activator 2A (guanylin) 2.99886
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.97349
MEF2C myocyte enhancer factor 2C 2.95153
ADPRH ADP-ribosylarginine hydrolase 2.9451
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.90887
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.87998
UTRN utrophin 2.84729
GRAMD4 GRAM domain containing 4 2.84351
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 2.81577
MX1 MX dynamin-like GTPase 1 2.79479
SLC26A2 solute carrier family 26 (anion exchanger), member 2 2.76165
GLOD4 glyoxalase domain containing 4 2.75025
SCNN1B sodium channel, non voltage gated 1 beta subunit 2.74721
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4 2.74716
CETP cholesteryl ester transfer protein, plasma 2.73727
CHP2 calcineurin-like EF-hand protein 2 2.72967
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 2.70859
ZEB2 zinc finger E-box binding homeobox 2 2.67132
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) 2.67112
BRCA1 breast cancer 1, early onset 2.651
PRELP proline/arginine-rich end leucine-rich repeat protein 2.64879
LY9 lymphocyte antigen 9 2.6333
TBPL1 TBP-like 1 2.63064
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.61147
SLC44A4 solute carrier family 44, member 4 2.60419
HLA-DRA major histocompatibility complex, class II, DR alpha 2.60393
MLH3 mutL homolog 3 2.59996
GMIP GEM interacting protein 2.59597
IRF5 interferon regulatory factor 5 2.59435
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 2.58081
MIA melanoma inhibitory activity 2.55647
MAP3K10 mitogen-activated protein kinase kinase kinase 10 2.55513
DNMBP dynamin binding protein 2.54883
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 2.5375
UBQLN2 ubiquilin 2 2.52528
CLDN15 claudin 15 2.52493
KIF15 kinesin family member 15 2.52453
ABR active BCR-related 2.52272
MACIR macrophage immunometabolism regulator 2.50403
ARID5B AT rich interactive domain 5B (MRF1-like) 2.49872
PRKCZ protein kinase C, zeta 2.48424
CCDC170 coiled-coil domain containing 170 2.47322
TIAM1 T-cell lymphoma invasion and metastasis 1 2.47244
MYLK myosin light chain kinase 2.47244
OR10H1 olfactory receptor, family 10, subfamily H, member 1 2.46924
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 2.44701
COPS7A COP9 signalosome subunit 7A 2.43398
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 2.43237
TUBA4B tubulin, alpha 4b 2.42447
RBL1 retinoblastoma-like 1 2.41549
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 2.41025
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 2.40226
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.39269
C1QTNF3 C1q and tumor necrosis factor related protein 3 2.39254
IHH indian hedgehog 2.39239
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.39227
TSEN2 TSEN2 tRNA splicing endonuclease subunit 2.38919
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.38537
CAPN5 calpain 5 2.37923
STAT2 signal transducer and activator of transcription 2, 113kDa 2.37837
AQP8 aquaporin 8 2.37727
ZG16 zymogen granule protein 16 2.3751
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13 2.37201
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 2.36528
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 2.36342
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 2.36238
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 2.36225
CHAF1B chromatin assembly factor 1, subunit B (p60) 2.35733
TMEM109 transmembrane protein 109 2.35665
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 2.35612
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 2.3496
SSUH2 ssu-2 homolog (C. elegans) 2.3496
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 2.34913
LIMD1 LIM domains containing 1 2.34124
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.33131
SLC26A3 solute carrier family 26 (anion exchanger), member 3 2.32185
LOC107987462 leukocyte immunoglobulin-like receptor subfamily B member 3 2.31601
NR1I2 nuclear receptor subfamily 1, group I, member 2 2.31525
PDPK1 3-phosphoinositide dependent protein kinase 1 2.31147
PEAK1 pseudopodium-enriched atypical kinase 1 2.31118
REM1 RAS (RAD and GEM)-like GTP-binding 1 2.30681
NAGK N-acetylglucosamine kinase 2.30447
GPR153 G protein-coupled receptor 153 2.3019
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 2.29755
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 2.29613
RGS11 regulator of G-protein signaling 11 2.29585
EP400 E1A binding protein p400 2.28913
HMGA2 high mobility group AT-hook 2 2.28877
SECISBP2 SECIS binding protein 2 2.28692
MATN4 matrilin 4 2.28539
EXD3 exonuclease 3'-5' domain containing 3 2.2852
CCL15 chemokine (C-C motif) ligand 15 2.28466
TACC1 transforming, acidic coiled-coil containing protein 1 2.28458
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 2.28217
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 2.27877
LMTK1 lemur tail kinase 1 2.27695
IFFO1 intermediate filament family orphan 1 2.27525
EVC Ellis van Creveld protein 2.27466
MERTK MER proto-oncogene, tyrosine kinase 2.27177
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.26257
PDLIM1 PDZ and LIM domain 1 2.25945
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 2.25714
RIOX1 ribosomal oxygenase 1 2.2534
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 2.25048
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 2.24246
MPPED1 metallophosphoesterase domain containing 1 2.23999
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.2376
INTS9 integrator complex subunit 9 2.23725
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 2.2354
HBA1 hemoglobin, alpha 1 2.23028
EDNRB endothelin receptor type B 2.22919
TASL TLR adaptor interacting with endolysosomal SLC15A4 2.22579
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2 2.22566
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2.22045
GNA14 guanine nucleotide binding protein (G protein), alpha 14 2.21742
CLCA1 chloride channel accessory 1 2.21692
FAM222B family with sequence similarity 222, member B 2.21621
ZNF536 zinc finger protein 536 2.2135
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 2.21099
OR1F1 olfactory receptor, family 1, subfamily F, member 1 2.21074
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.20887
RNASE12 ribonuclease, RNase A family, 12 (non-active) 2.19353
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 2.18779
MRLN myoregulin 2.18517
GOLGA3 golgin A3 2.18493
GIPC2 GIPC PDZ domain containing family, member 2 2.18279
SLAMF1 signaling lymphocytic activation molecule family member 1 2.18202
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 2.18149
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 2.18056
IL2RA interleukin 2 receptor, alpha 2.17854
MUL1 mitochondrial E3 ubiquitin protein ligase 1 2.17723
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 2.17646
GALR3 galanin receptor 3 2.1763
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 2.17571
SERINC5 serine incorporator 5 2.17496
HSPA1A heat shock 70kDa protein 1A 2.17454
GUCA2B guanylate cyclase activator 2B (uroguanylin) 2.17228
CCL24 chemokine (C-C motif) ligand 24 2.1697
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) 2.16664
PRR5 proline rich 5 (renal) 2.16593
RASA4 RAS p21 protein activator 4 2.16553
ZC3H14 zinc finger CCCH-type containing 14 2.16366
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 2.16139
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 2.16076
MELTF melanotransferrin 2.15606
FCN1 ficolin (collagen/fibrinogen domain containing) 1 2.15138
HDAC11 histone deacetylase 11 2.15127
DNAH9 dynein, axonemal, heavy chain 9 2.14268
TCTN3 tectonic family member 3 2.14055
TPSG1 tryptase gamma 1 2.13784
PHACTR1 phosphatase and actin regulator 1 2.13342
TMEM50A transmembrane protein 50A 2.1305
BARX2 BARX homeobox 2 2.12799
CLMN calmin (calponin-like, transmembrane) 2.12731
KLHL29 kelch-like family member 29 2.12544
CHMP6 charged multivesicular body protein 6 2.12505
TOM1L2 target of myb1-like 2 (chicken) 2.11968
CASP5 caspase 5, apoptosis-related cysteine peptidase 2.11811
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 2.11293
SSTR1 somatostatin receptor 1 2.1129
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 2.11146
FCGRT Fc fragment of IgG, receptor, transporter, alpha 2.11128
PADI3 peptidyl arginine deiminase, type III 2.1099
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 2.10904
KLHL21 kelch-like family member 21 2.10763
NOLC1 nucleolar and coiled-body phosphoprotein 1 2.107
CDHR5 cadherin-related family member 5 2.10388
GK glycerol kinase 2.10277
CBARP CACN subunit beta associated regulatory protein 2.09954
HACL2 2-hydroxyacyl-CoA lyase 2 2.09905
CCL14 chemokine (C-C motif) ligand 14 2.09771
ZNF324B zinc finger protein 324B 2.09764
KRT20 keratin 20, type I 2.09526
TRAIP TRAF interacting protein 2.09493
LOC100652777 group 10 secretory phospholipase A2-like 2.09482
MEGF9 multiple EGF-like-domains 9 2.09466
CPZ carboxypeptidase Z 2.09442
GCG glucagon 2.09373
GPC3 glypican 3 2.08536
BCL10 B-cell CLL/lymphoma 10 2.08531
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 2.08408
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 2.08249
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 2.08177
POMT2 protein-O-mannosyltransferase 2 2.08146
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1 2.0808
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1) 2.08007
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.07858
CLCN2 chloride channel, voltage-sensitive 2 2.07631
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 2.07425
MEPE matrix extracellular phosphoglycoprotein 2.07405
SV2C synaptic vesicle glycoprotein 2C 2.07262
TTLL7 tubulin tyrosine ligase-like family member 7 2.07079
PYY peptide YY 2.06328
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow 2.06312
PCDHB12 protocadherin beta 12 2.06225
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.06132
EPS8L3 EPS8-like 3 2.06115
CEP131 centrosomal protein 131kDa 2.05582
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 2.05407
MYO19 myosin XIX 2.05273
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 2.0498
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 2.0438
TCIM transcriptional and immune response regulator 2.04303
CCRL2 chemokine (C-C motif) receptor-like 2 2.04197
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 2.04073
SYTL3 synaptotagmin-like 3 2.0368
DEPDC5 DEP domain containing 5 2.03217
MYO9B myosin IXB 2.03041
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 2.03034
SQOR sulfide quinone oxidoreductase 2.03025
KCTD5 potassium channel tetramerization domain containing 5 2.02939
DCLRE1C DNA cross-link repair 1C 2.02622
SACS sacsin molecular chaperone 2.0262
RNF144A ring finger protein 144A 2.02542
FFAR2 free fatty acid receptor 2 2.024
FAR2 fatty acyl CoA reductase 2 2.02274
MUC4 mucin 4, cell surface associated 2.02241
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 2.01824
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 2.01264
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 2.01249
DUS2 dihydrouridine synthase 2 2.01238
POLK polymerase (DNA directed) kappa 2.01098
BRME1 break repair meiotic recombinase recruitment factor 1 2.00938
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2 2.00794
MEP1A meprin A, alpha (PABA peptide hydrolase) 2.00723
XDH xanthine dehydrogenase 2.00661
BMP6 bone morphogenetic protein 6 2.00636
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 2.00487
A4GALT alpha 1,4-galactosyltransferase 2.0048
BMP3 bone morphogenetic protein 3 2.00469
CCL1 chemokine (C-C motif) ligand 1 2.00416
ASIC4 acid sensing (proton gated) ion channel family member 4 2.00398
LRRC19 leucine rich repeat containing 19 2.00323
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 2.00261
PTCRA pre T-cell antigen receptor alpha 2.00177
MNMIP1 manchette microtubule inner protein 1 2.00117
AMN amnion associated transmembrane protein 2.00096
MMP14 matrix metallopeptidase 14 (membrane-inserted) 2.00027

decreased expression

Symbol Name Standardized Value
ANKRD10 ankyrin repeat domain 10 -5.61315
NPDC1 neural proliferation, differentiation and control, 1 -5.45864
UBE3C ubiquitin protein ligase E3C -4.68639
TIMP1 TIMP metallopeptidase inhibitor 1 -4.56004
CCNB2 cyclin B2 -4.08907
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.94831
GOLT1B golgi transport 1B -3.90939
NUSAP1 nucleolar and spindle associated protein 1 -3.88465
DNM1L dynamin 1-like -3.84452
DCK deoxycytidine kinase -3.69694
RAB5IF RAB5 interacting factor -3.35157
ADI1 acireductone dioxygenase 1 -3.27342
INSIG1 insulin induced gene 1 -3.18968
TOM1L1 target of myb1 (chicken)-like 1 -3.15927
GTPBP8 GTP-binding protein 8 (putative) -3.15906
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -3.14212
COTL1 coactosin-like F-actin binding protein 1 -3.09094
SEC61G Sec61 gamma subunit -3.0575
ORC4 origin recognition complex, subunit 4 -3.00563
TUBA4A tubulin, alpha 4a -2.99623
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa -2.99062
NOSIP nitric oxide synthase interacting protein -2.9387
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough -2.92249
NMU neuromedin U -2.8715
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria -2.83074
APMAP adipocyte plasma membrane associated protein -2.81422
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -2.79288
ZDHHC4 zinc finger, DHHC-type containing 4 -2.74277
S100A4 S100 calcium binding protein A4 -2.73284
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -2.66909
CCNB1 cyclin B1 -2.65479
DDIT4 DNA-damage-inducible transcript 4 -2.63324
YME1L1 YME1-like 1 ATPase -2.62442
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -2.62085
SGK1 serum/glucocorticoid regulated kinase 1 -2.61781
YBX3 Y box binding protein 3 -2.61692
LMAN2L lectin, mannose-binding 2-like -2.60374
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 -2.60231
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.57668
ETFA electron-transfer-flavoprotein, alpha polypeptide -2.56934
AP2S1 adaptor-related protein complex 2, sigma 1 subunit -2.56611
LAP3 leucine aminopeptidase 3 -2.55541
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 -2.54501
AARS1 alanyl-tRNA synthetase 1 -2.53674
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa -2.53275
ANXA2 annexin A2 -2.52689
PFN1 profilin 1 -2.51696
HAMP hepcidin antimicrobial peptide -2.49548
MAP2K1 mitogen-activated protein kinase kinase 1 -2.48985
SLC35F2 solute carrier family 35, member F2 -2.48608
COQ9 coenzyme Q9 -2.47666
MRPS15 mitochondrial ribosomal protein S15 -2.47246
HMGN2 high mobility group nucleosomal binding domain 2 -2.45785
MAIP1 matrix AAA peptidase interacting protein 1 -2.45119
MRPL19 mitochondrial ribosomal protein L19 -2.43273
TRIAP1 TP53 regulated inhibitor of apoptosis 1 -2.4312
PRSS8 protease, serine, 8 -2.42003
COPZ1 coatomer protein complex, subunit zeta 1 -2.41141
IFRD1 interferon-related developmental regulator 1 -2.38365
SMNDC1 survival motor neuron domain containing 1 -2.37469
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 -2.35888
ACTR6 ARP6 actin-related protein 6 homolog (yeast) -2.35465
BUD31 BUD31 homolog (S. cerevisiae) -2.34027
GLRX glutaredoxin (thioltransferase) -2.33097
KATNBL1 katanin p80 subunit B-like 1 -2.3254
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -2.3239
OVOL2 ovo-like zinc finger 2 -2.31834
ATRAID all-trans retinoic acid-induced differentiation factor -2.31631
CLTC clathrin, heavy chain (Hc) -2.31115
RHOG ras homolog family member G -2.31038
MRPL58 mitochondrial ribosomal protein L58 -2.30839
MRPS2 mitochondrial ribosomal protein S2 -2.30191
HINT1 histidine triad nucleotide binding protein 1 -2.29173
INTS12 integrator complex subunit 12 -2.28347
ACO1 aconitase 1, soluble -2.27763
NUP37 nucleoporin 37kDa -2.27701
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -2.27163
COG2 component of oligomeric golgi complex 2 -2.26387
PPID peptidylprolyl isomerase D -2.25828
ATP5PD ATP synthase peripheral stalk subunit d -2.24495
GDF15 growth differentiation factor 15 -2.24419
RHOB ras homolog family member B -2.23865
BMAL2 basic helix-loop-helix ARNT like 2 -2.23863
GNPAT glyceronephosphate O-acyltransferase -2.23481
RAD51C RAD51 paralog C -2.21951
SAE1 SUMO1 activating enzyme subunit 1 -2.20911
RAP2C RAP2C, member of RAS oncogene family -2.20888
ATP5MC3 ATP synthase membrane subunit c locus 3 -2.20569
MRPS22 mitochondrial ribosomal protein S22 -2.20531
CIAO2B cytosolic iron-sulfur assembly component 2B -2.20237
TALDO1 transaldolase 1 -2.19485
OIP5 Opa interacting protein 5 -2.19295
EMC6 ER membrane protein complex subunit 6 -2.19018
HOXB3 homeobox B3 -2.18617
ITFG1 integrin alpha FG-GAP repeat containing 1 -2.1762
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.17544
RNF139 ring finger protein 139 -2.17504
MRPS10 mitochondrial ribosomal protein S10 -2.17434
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 -2.1737
PPIE peptidylprolyl isomerase E (cyclophilin E) -2.1669
AKIP1 A kinase (PRKA) interacting protein 1 -2.15907
PITX1 paired-like homeodomain 1 -2.14512
AMZ2 archaelysin family metallopeptidase 2 -2.14027
MTO1 mitochondrial tRNA translation optimization 1 -2.13968
KRT18 keratin 18, type I -2.13385
SNAP29 synaptosomal-associated protein, 29kDa -2.13297
EMC7 ER membrane protein complex subunit 7 -2.13004
NOP10 NOP10 ribonucleoprotein -2.11915
TKT transketolase -2.11785
TES testin LIM domain protein -2.11746
MTFR1 mitochondrial fission regulator 1 -2.112
RAB13 RAB13, member RAS oncogene family -2.11024
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -2.10706
POMP proteasome maturation protein -2.1045
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa -2.10055
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -2.09968
NQO2 NAD(P)H dehydrogenase, quinone 2 -2.08871
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -2.07979
GZMK granzyme K (granzyme 3; tryptase II) -2.07886
DEPDC1 DEP domain containing 1 -2.07037
HSPA4L heat shock 70kDa protein 4-like -2.06865
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.06664
TARBP2 TAR (HIV-1) RNA binding protein 2 -2.0662
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -2.05575
PPA2 pyrophosphatase (inorganic) 2 -2.05422
METTL17 methyltransferase like 17 -2.05032
CCNC cyclin C -2.04813
MRPS35 mitochondrial ribosomal protein S35 -2.0473
DCP2 decapping mRNA 2 -2.04175
ABHD10 abhydrolase domain containing 10 -2.0383
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -2.03174
GUK1 guanylate kinase 1 -2.02951
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.02861
RARS1 arginyl-tRNA synthetase 1 -2.02742
LDHD lactate dehydrogenase D -2.02631
MTX2 metaxin 2 -2.02553
SEC24B SEC24 family member B -2.02394
RNASE6 ribonuclease, RNase A family, k6 -2.0215
DHRS7 dehydrogenase/reductase (SDR family) member 7 -2.02057
GOLT1A golgi transport 1A -2.01776
GTF2A2 general transcription factor IIA, 2, 12kDa -2.01124
MKNK2 MAP kinase interacting serine/threonine kinase 2 -2.01062
CARS1 cysteinyl-tRNA synthetase 1 -2.00755
MCTS1 malignant T cell amplified sequence 1 -2.00528
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 -2.00105