CRCGN016_MCF10A.TP53.M_24H:K13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,2-dibromo-3-chloropropane 99.3 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

23 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:K13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GPER1 G protein-coupled estrogen receptor 1 4.70411
CNRIP1 cannabinoid receptor interacting protein 1 4.11964
CCP110 centriolar coiled coil protein 110kDa 3.79286
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.76081
CIAO3 cytosolic iron-sulfur assembly component 3 3.39696
TBX2 T-box 2 3.25478
HBA1 hemoglobin, alpha 1 3.13749
TLCD3A TLC domain containing 3A 2.41812
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.37085
HLA-DRA major histocompatibility complex, class II, DR alpha 2.26347
WIF1 WNT inhibitory factor 1 2.24041
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.06727

decreased expression

Symbol Name Standardized Value
NPDC1 neural proliferation, differentiation and control, 1 -4.26069
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.59067
KIF14 kinesin family member 14 -3.39397
COTL1 coactosin-like F-actin binding protein 1 -3.37413
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.1271
FASTKD5 FAST kinase domains 5 -3.1193
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -3.08625
PFN1 profilin 1 -2.53171
BASP1 brain abundant, membrane attached signal protein 1 -2.43696
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -2.30349
APOA4 apolipoprotein A-IV -2.13524