CRCGN016_MCF10A.TP53.M_24H:K14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,2-dibromo-3-chloropropane 33.1 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

21 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:K14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KIF5C kinesin family member 5C 3.30436
BACE2 beta-site APP-cleaving enzyme 2 3.0213
IGHMBP2 immunoglobulin mu binding protein 2 3.00631
CNRIP1 cannabinoid receptor interacting protein 1 2.90108
SATB1 SATB homeobox 1 2.25229

decreased expression

Symbol Name Standardized Value
SLC35F2 solute carrier family 35, member F2 -4.2307
ADI1 acireductone dioxygenase 1 -4.17958
DHRS7 dehydrogenase/reductase (SDR family) member 7 -3.98471
BID BH3 interacting domain death agonist -3.62716
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -3.5646
COTL1 coactosin-like F-actin binding protein 1 -3.21712
CANT1 calcium activated nucleotidase 1 -2.96035
ATG3 autophagy related 3 -2.8303
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.78518
GDF15 growth differentiation factor 15 -2.51973
SGK1 serum/glucocorticoid regulated kinase 1 -2.50889
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.47075
RAI14 retinoic acid induced 14 -2.39608
BPHL biphenyl hydrolase-like (serine hydrolase) -2.32884
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound -2.06463
MT1X metallothionein 1X -2.02147