CRCGN016_MCF10A.TP53.M_24H:K15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,2-dibromo-3-chloropropane 11.03 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:K15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 3.80864
CXCR4 chemokine (C-X-C motif) receptor 4 3.59921
HMOX1 heme oxygenase 1 3.39667
GATA3 GATA binding protein 3 3.331
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.21367
ADGRE5 adhesion G protein-coupled receptor E5 3.14553
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 3.08804
HBA1 hemoglobin, alpha 1 2.37836
CNRIP1 cannabinoid receptor interacting protein 1 2.37123
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.366
FGFR4 fibroblast growth factor receptor 4 2.26278

decreased expression

Symbol Name Standardized Value
SMNDC1 survival motor neuron domain containing 1 -4.7525
GADD45B growth arrest and DNA-damage-inducible, beta -3.47165
KIF14 kinesin family member 14 -3.029
PRPF4 pre-mRNA processing factor 4 -2.68519
CYCS cytochrome c, somatic -2.33229
SGK1 serum/glucocorticoid regulated kinase 1 -2.22258
RUSC2 RUN and SH3 domain containing 2 -2.20844
HMG20B high mobility group 20B -2.01272
RPA3 replication protein A3, 14kDa -2.00219