CRCGN016_MCF10A.TP53.M_24H:K16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acetaldehyde 103.79 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

30 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:K16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HMOX1 heme oxygenase 1 3.84587
BZW2 basic leucine zipper and W2 domains 2 3.80295
DHRS2 dehydrogenase/reductase (SDR family) member 2 3.31242
FGFR4 fibroblast growth factor receptor 4 3.04179
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.70743
SNAP25 synaptosomal-associated protein, 25kDa 2.46659
E2F2 E2F transcription factor 2 2.41366
HBA1 hemoglobin, alpha 1 2.38101
KIF5C kinesin family member 5C 2.20045
GATA3 GATA binding protein 3 2.04699
ACAA1 acetyl-CoA acyltransferase 1 2.04646

decreased expression

Symbol Name Standardized Value
SGK1 serum/glucocorticoid regulated kinase 1 -5.16332
TES testin LIM domain protein -3.82108
HMG20B high mobility group 20B -3.60224
TUBA4A tubulin, alpha 4a -3.44492
FASTKD5 FAST kinase domains 5 -3.30506
CAB39 calcium binding protein 39 -3.29651
CTNND1 catenin (cadherin-associated protein), delta 1 -3.19678
KIF14 kinesin family member 14 -3.15771
BID BH3 interacting domain death agonist -2.99489
DHRS7 dehydrogenase/reductase (SDR family) member 7 -2.86303
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -2.53609
PANK2 pantothenate kinase 2 -2.50591
DDRGK1 DDRGK domain containing 1 -2.46457
TIMP1 TIMP metallopeptidase inhibitor 1 -2.32562
CRNKL1 crooked neck pre-mRNA splicing factor 1 -2.28691
PCNA proliferating cell nuclear antigen -2.22695
MT1X metallothionein 1X -2.20243
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.1107
CANT1 calcium activated nucleotidase 1 -2.10298