CRCGN016_MCF10A.TP53.M_24H:K18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acetaldehyde 11.53 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:K18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CHMP6 charged multivesicular body protein 6 4.05735
ACAA1 acetyl-CoA acyltransferase 1 3.17732
PPARG peroxisome proliferator-activated receptor gamma 2.85815
GET1 guided entry of tail-anchored proteins factor 1 2.18364
CREG1 cellular repressor of E1A-stimulated genes 1 2.08818

decreased expression

Symbol Name Standardized Value
HAT1 histone acetyltransferase 1 -3.47787
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.43394
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.67051
SGK1 serum/glucocorticoid regulated kinase 1 -2.63292
PRPF4 pre-mRNA processing factor 4 -2.55762
SLC35B1 solute carrier family 35, member B1 -2.5336
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.27347
TXNRD1 thioredoxin reductase 1 -2.26065
KRT14 keratin 14, type I -2.14081