CRCGN016_MCF10A.TP53.M_24H:K19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description cresol 99.69 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

48 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:K19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 5.07736
SSBP2 single-stranded DNA binding protein 2 4.71685
TBX2 T-box 2 4.63354
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 4.43931
SNAP25 synaptosomal-associated protein, 25kDa 4.42473
PEX11A peroxisomal biogenesis factor 11 alpha 4.33701
BAMBI BMP and activin membrane-bound inhibitor 4.14179
CETN3 centrin, EF-hand protein, 3 3.82665
SIRT3 sirtuin 3 3.77804
GARRE1 granule associated Rac and RHOG effector 1 2.81451
SNAP91 synaptosomal-associated protein, 91kDa 2.75289
MRPL23 mitochondrial ribosomal protein L23 2.73587
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 2.69196
COQ8A coenzyme Q8A 2.67704
BOLA1 bolA family member 1 2.61712
CADM1 cell adhesion molecule 1 2.60629
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.57692
RIC8A RIC8 guanine nucleotide exchange factor A 2.49233
TLCD3A TLC domain containing 3A 2.44049
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 2.39726
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal 2.33079
SASH3 SAM and SH3 domain containing 3 2.2962
ACAA1 acetyl-CoA acyltransferase 1 2.21728
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 2.18857
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2) 2.13052
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 2.06047
DEAF1 DEAF1 transcription factor 2.05222
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.04671
DNM3 dynamin 3 2.02783
STMN2 stathmin 2 2.01487

decreased expression

Symbol Name Standardized Value
KIF14 kinesin family member 14 -4.65221
TNIP1 TNFAIP3 interacting protein 1 -4.56859
PRPF4 pre-mRNA processing factor 4 -4.42081
BASP1 brain abundant, membrane attached signal protein 1 -3.83435
TMEM268 transmembrane protein 268 -2.74584
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 -2.65822
FKBP15 FK506 binding protein 15, 133kDa -2.54365
RAI14 retinoic acid induced 14 -2.40305
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -2.34585
KCNK1 potassium channel, two pore domain subfamily K, member 1 -2.15373
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 -2.14858
USP3 ubiquitin specific peptidase 3 -2.14515
TOR1B torsin family 1, member B (torsin B) -2.14206
ACTG2 actin, gamma 2, smooth muscle, enteric -2.13267
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -2.1155
RFK riboflavin kinase -2.09905
IGFBP7 insulin-like growth factor binding protein 7 -2.08791
CDCP1 CUB domain containing protein 1 -2.0073