CRCGN016_MCF10A.TP53.M_24H:K21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description cresol 11.08 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:K21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CNRIP1 cannabinoid receptor interacting protein 1 5.07595
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 4.32233
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 4.05695
EAPP E2F-associated phosphoprotein 3.83254
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.51433
ZNF586 zinc finger protein 586 3.1814
MAP7 microtubule-associated protein 7 2.93311
SNAP25 synaptosomal-associated protein, 25kDa 2.47115

decreased expression

Symbol Name Standardized Value
CD58 CD58 molecule -3.2177
MALT1 MALT1 paracaspase -2.89879
KRT14 keratin 14, type I -2.82592
GDF15 growth differentiation factor 15 -2.80533
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.66361
CAPN2 calpain 2, (m/II) large subunit -2.12884
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.03113