CRCGN016_MCF10A.TP53.M_24H:L05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hydrazine sulfate 33.27 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

84 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:L05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KCTD5 potassium channel tetramerization domain containing 5 5.5763
CCDC92 coiled-coil domain containing 92 5.32295
SPAG4 sperm associated antigen 4 5.16675
MAMLD1 mastermind-like domain containing 1 4.4607
TSPAN6 tetraspanin 6 4.11777
NUP205 nucleoporin 205kDa 3.8112
SYNGAP1 synaptic Ras GTPase activating protein 1 3.21635
CYREN cell cycle regulator of NHEJ 2.5708
WIF1 WNT inhibitory factor 1 2.45545
CUL1 cullin 1 2.409
ACAA1 acetyl-CoA acyltransferase 1 2.3042
GLRB glycine receptor, beta 2.27805
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 2.2164
PEX12 peroxisomal biogenesis factor 12 2.17455
HELZ helicase with zinc finger 2.1571
BHLHE40 basic helix-loop-helix family, member e40 2.14068
LTF lactotransferrin 2.13765
MSRA methionine sulfoxide reductase A 2.11815
ACSS3 acyl-CoA synthetase short-chain family member 3 2.11515
NME4 NME/NM23 nucleoside diphosphate kinase 4 2.09585
TMEM255A transmembrane protein 255A 2.093
SFTPD surfactant protein D 2.07135
ADRB2 adrenoceptor beta 2, surface 2.07035
DNM1L dynamin 1-like 2.06855
RBM28 RNA binding motif protein 28 2.0669
TRIM24 tripartite motif containing 24 2.05685
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 2.0553
PACRG PARK2 co-regulated 2.04802
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 2.03915
VSNL1 visinin-like 1 2.03583
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.03305
DGKG diacylglycerol kinase, gamma 90kDa 2.0312
CREB3L2 cAMP responsive element binding protein 3-like 2 2.0221
GYS1 glycogen synthase 1 (muscle) 2.01425
MAGED1 melanoma antigen family D1 2.00995

decreased expression

Symbol Name Standardized Value
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -6.07095
KIF14 kinesin family member 14 -5.3749
BASP1 brain abundant, membrane attached signal protein 1 -5.27525
THAP11 THAP domain containing 11 -5.17875
ENOPH1 enolase-phosphatase 1 -4.37335
CRK v-crk avian sarcoma virus CT10 oncogene homolog -4.1609
TOR1A torsin family 1, member A (torsin A) -3.55447
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -3.12555
MXRA8 matrix-remodelling associated 8 -3.0293
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -2.8217
BPHL biphenyl hydrolase-like (serine hydrolase) -2.76615
CXCL14 chemokine (C-X-C motif) ligand 14 -2.6338
RNF13 ring finger protein 13 -2.53688
ZNF281 zinc finger protein 281 -2.50975
PDGFRL platelet-derived growth factor receptor-like -2.4762
NUP93 nucleoporin 93kDa -2.4733
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 -2.34495
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 -2.34075
STIL SCL/TAL1 interrupting locus -2.3359
RPN1 ribophorin I -2.31785
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase -2.31215
CBR3 carbonyl reductase 3 -2.25865
STK25 serine/threonine kinase 25 -2.24595
IRX4 iroquois homeobox 4 -2.21585
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -2.2122
NINJ1 ninjurin 1 -2.1983
HEXB hexosaminidase B (beta polypeptide) -2.19535
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 -2.19295
EVI2A ecotropic viral integration site 2A -2.1861
STXBP2 syntaxin binding protein 2 -2.18495
ATXN3 ataxin 3 -2.1738
DEGS1 delta(4)-desaturase, sphingolipid 1 -2.16995
RRAGC Ras-related GTP binding C -2.166
IGFBP7 insulin-like growth factor binding protein 7 -2.15027
MTARC1 mitochondrial amidoxime reducing component 1 -2.12685
FMNL1 formin-like 1 -2.0824
KANK3 KN motif and ankyrin repeat domains 3 -2.0645
PCNP PEST proteolytic signal containing nuclear protein -2.06115
MEOX1 mesenchyme homeobox 1 -2.0471
TKT transketolase -2.04577
OLFML2A olfactomedin-like 2A -2.04355
RBBP5 retinoblastoma binding protein 5 -2.03845
RWDD3 RWD domain containing 3 -2.0296
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -2.02435
LMO2 LIM domain only 2 (rhombotin-like 1) -2.0221
USB1 U6 snRNA biogenesis 1 -2.01695
CCDC85C coiled-coil domain containing 85C -2.01545
OMD osteomodulin -2.0134
SBDS Shwachman-Bodian-Diamond syndrome -2.0026