CRCGN016_MCF10A.TP53.M_24H:L06 Gene Set
Genes
33 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:L06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
KLHL21
|
kelch-like family member 21
|
4.80158
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
4.75518
|
|
ANO10
|
anoctamin 10
|
4.74242
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
3.39163
|
|
SSR3
|
signal sequence receptor, gamma (translocon-associated protein gamma)
|
3.03984
|
|
RFC5
|
replication factor C (activator 1) 5, 36.5kDa
|
2.89042
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.59617
|
|
EIF5AL1
|
eukaryotic translation initiation factor 5A-like 1
|
2.40722
|
|
MTA2
|
metastasis associated 1 family, member 2
|
2.37286
|
|
HNRNPL
|
heterogeneous nuclear ribonucleoprotein L
|
2.33973
|
|
WDR76
|
WD repeat domain 76
|
2.28609
|
|
GSR
|
glutathione reductase
|
2.07616
|
|
NUTF2
|
nuclear transport factor 2
|
2.0678
|
|
SQOR
|
sulfide quinone oxidoreductase
|
2.0059
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
KIF14
|
kinesin family member 14
|
-6.85117
|
|
BASP1
|
brain abundant, membrane attached signal protein 1
|
-4.81885
|
|
TUBB6
|
tubulin, beta 6 class V
|
-4.54078
|
|
TIMP1
|
TIMP metallopeptidase inhibitor 1
|
-3.92522
|
|
COTL1
|
coactosin-like F-actin binding protein 1
|
-3.44687
|
|
CCNB2
|
cyclin B2
|
-2.95907
|
|
ATG3
|
autophagy related 3
|
-2.87649
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-2.84302
|
|
VAT1
|
vesicle amine transport 1
|
-2.5996
|
|
ATF5
|
activating transcription factor 5
|
-2.43193
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.36472
|
|
CAPN2
|
calpain 2, (m/II) large subunit
|
-2.30021
|
|
LYPLA1
|
lysophospholipase I
|
-2.21546
|
|
NECAP2
|
NECAP endocytosis associated 2
|
-2.17177
|
|
ASPM
|
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
|
-2.13929
|
|
DOK2
|
docking protein 2, 56kDa
|
-2.138
|
|
EMP3
|
epithelial membrane protein 3
|
-2.10614
|
|
HPS5
|
Hermansky-Pudlak syndrome 5
|
-2.06624
|
|
CFP
|
complement factor properdin
|
-2.01334
|