CRCGN016_MCF10A.TP53.M_24H:L06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hydrazine sulfate 11.09 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

33 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:L06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KLHL21 kelch-like family member 21 4.80158
CASP2 caspase 2, apoptosis-related cysteine peptidase 4.75518
ANO10 anoctamin 10 4.74242
CXCR4 chemokine (C-X-C motif) receptor 4 3.39163
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 3.03984
RFC5 replication factor C (activator 1) 5, 36.5kDa 2.89042
MCUR1 mitochondrial calcium uniporter regulator 1 2.59617
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2.40722
MTA2 metastasis associated 1 family, member 2 2.37286
HNRNPL heterogeneous nuclear ribonucleoprotein L 2.33973
WDR76 WD repeat domain 76 2.28609
GSR glutathione reductase 2.07616
NUTF2 nuclear transport factor 2 2.0678
SQOR sulfide quinone oxidoreductase 2.0059

decreased expression

Symbol Name Standardized Value
KIF14 kinesin family member 14 -6.85117
BASP1 brain abundant, membrane attached signal protein 1 -4.81885
TUBB6 tubulin, beta 6 class V -4.54078
TIMP1 TIMP metallopeptidase inhibitor 1 -3.92522
COTL1 coactosin-like F-actin binding protein 1 -3.44687
CCNB2 cyclin B2 -2.95907
ATG3 autophagy related 3 -2.87649
ACOT9 acyl-CoA thioesterase 9 -2.84302
VAT1 vesicle amine transport 1 -2.5996
ATF5 activating transcription factor 5 -2.43193
KDM3A lysine (K)-specific demethylase 3A -2.36472
CAPN2 calpain 2, (m/II) large subunit -2.30021
LYPLA1 lysophospholipase I -2.21546
NECAP2 NECAP endocytosis associated 2 -2.17177
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.13929
DOK2 docking protein 2, 56kDa -2.138
EMP3 epithelial membrane protein 3 -2.10614
HPS5 Hermansky-Pudlak syndrome 5 -2.06624
CFP complement factor properdin -2.01334