CRCGN016_MCF10A.TP53.M_24H:L07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description fd & c blue no. 2 99.8 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:L07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AMDHD2 amidohydrolase domain containing 2 4.88443
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.14019
MAMLD1 mastermind-like domain containing 1 3.45527
KIF5C kinesin family member 5C 2.9959
MNAT1 MNAT CDK-activating kinase assembly factor 1 2.85033
TBX2 T-box 2 2.63177
SPAG4 sperm associated antigen 4 2.53046
BAMBI BMP and activin membrane-bound inhibitor 2.51122
RIC8A RIC8 guanine nucleotide exchange factor A 2.42809
SIRT3 sirtuin 3 2.33597
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.29024
TPD52L2 tumor protein D52-like 2 2.15668
TAOK3 TAO kinase 3 2.03803

decreased expression

Symbol Name Standardized Value
GRWD1 glutamate-rich WD repeat containing 1 -3.81011
UFM1 ubiquitin-fold modifier 1 -3.75395
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -3.65379
TUBA4A tubulin, alpha 4a -2.48399
TKT transketolase -2.12233