CRCGN016_MCF10A.TP53.M_24H:L13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,2,3-trichloropropane 100.3 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

18 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:L13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.91471
SNAP25 synaptosomal-associated protein, 25kDa 4.87738
LAGE3 L antigen family, member 3 4.63656
PLS1 plastin 1 2.68222
ACAA1 acetyl-CoA acyltransferase 1 2.66816
LGMN legumain 2.47898
SYNGR3 synaptogyrin 3 2.41839
NSG2 neuronal vesicle trafficking associated 2 2.25112
RAB21 RAB21, member RAS oncogene family 2.15451
APTX aprataxin 2.06317
STMN2 stathmin 2 2.05791

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -5.10543
UFM1 ubiquitin-fold modifier 1 -4.97767
BID BH3 interacting domain death agonist -4.33075
PCNA proliferating cell nuclear antigen -3.9041
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -2.21825
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.19371
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit -2.02687