| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1,2,3-trichloropropane 33.43 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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79 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:L14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AMDHD2 | amidohydrolase domain containing 2 | 4.7101 |
| EAPP | E2F-associated phosphoprotein | 4.28372 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 4.15514 |
| KLHL21 | kelch-like family member 21 | 4.05501 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.99975 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.85227 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.45464 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.32938 |
| SRP54 | signal recognition particle 54kDa | 2.79441 |
| FAT1 | FAT atypical cadherin 1 | 2.79238 |
| CIDEB | cell death-inducing DFFA-like effector b | 2.79031 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.49878 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 2.46761 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 2.46628 |
| DOCK2 | dedicator of cytokinesis 2 | 2.43535 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.36726 |
| CORO1A | coronin, actin binding protein, 1A | 2.35339 |
| FN3KRP | fructosamine 3 kinase related protein | 2.34788 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 2.34324 |
| SCFD1 | sec1 family domain containing 1 | 2.29331 |
| GPATCH8 | G patch domain containing 8 | 2.23542 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 2.20893 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 | 2.20018 |
| HLF | hepatic leukemia factor | 2.16043 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 | 2.15626 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 2.15582 |
| ARL5A | ADP-ribosylation factor-like 5A | 2.15512 |
| XPC | xeroderma pigmentosum, complementation group C | 2.14113 |
| BNIP2 | BCL2/adenovirus E1B 19kDa interacting protein 2 | 2.13414 |
| ENO1 | enolase 1, (alpha) | 2.12818 |
| TBXA2R | thromboxane A2 receptor | 2.12203 |
| SCT | secretin | 2.08961 |
| CCL21 | chemokine (C-C motif) ligand 21 | 2.08913 |
| MBNL1 | muscleblind-like splicing regulator 1 | 2.06883 |
| TENT5A | terminal nucleotidyltransferase 5A | 2.06639 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 2.05717 |
| PDCD10 | programmed cell death 10 | 2.0395 |
| SATB1 | SATB homeobox 1 | 2.02871 |
| PER1 | period circadian clock 1 | 2.01815 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 2.00014 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TRAPPC3 | trafficking protein particle complex 3 | -4.07739 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.93695 |
| SLC35F2 | solute carrier family 35, member F2 | -3.75638 |
| RNF167 | ring finger protein 167 | -3.71327 |
| PRPF4 | pre-mRNA processing factor 4 | -3.6712 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) | -3.55299 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -3.47275 |
| HMG20B | high mobility group 20B | -3.34276 |
| PFN1 | profilin 1 | -3.30037 |
| COL4A1 | collagen, type IV, alpha 1 | -3.24818 |
| MSN | moesin | -3.12657 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -2.86211 |
| RPA3 | replication protein A3, 14kDa | -2.82065 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -2.80407 |
| VIM | vimentin | -2.6811 |
| UBE3C | ubiquitin protein ligase E3C | -2.65683 |
| NANS | N-acetylneuraminic acid synthase | -2.62842 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.62454 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -2.60845 |
| MRPS15 | mitochondrial ribosomal protein S15 | -2.58085 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -2.47647 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -2.45589 |
| PTK7 | protein tyrosine kinase 7 (inactive) | -2.33706 |
| WWC1 | WW and C2 domain containing 1 | -2.22509 |
| CLDN16 | claudin 16 | -2.16175 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) | -2.14787 |
| COL4A2 | collagen, type IV, alpha 2 | -2.14716 |
| ANXA13 | annexin A13 | -2.14164 |
| ZNF175 | zinc finger protein 175 | -2.11368 |
| CPT1B | carnitine palmitoyltransferase 1B (muscle) | -2.07904 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 | -2.07878 |
| NDUFA7 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa | -2.0637 |
| SDF2L1 | stromal cell-derived factor 2-like 1 | -2.06332 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | -2.05353 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase | -2.04193 |
| STK38 | serine/threonine kinase 38 | -2.03528 |
| GUSB | glucuronidase, beta | -2.0205 |
| UPK1A | uroplakin 1A | -2.01635 |
| ZMYM4 | zinc finger, MYM-type 4 | -2.00818 |
