CRCGN016_MCF10A.TP53.M_24H:L15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,2,3-trichloropropane 11.14 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:L15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.32938
AMDHD2 amidohydrolase domain containing 2 3.09202
AGR2 anterior gradient 2 2.76006
CCNA1 cyclin A1 2.71149
CNRIP1 cannabinoid receptor interacting protein 1 2.66495
CCL2 chemokine (C-C motif) ligand 2 2.57985
ACLY ATP citrate lyase 2.42895
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.30819
RFC5 replication factor C (activator 1) 5, 36.5kDa 2.1521

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -6.8937
GTPBP8 GTP-binding protein 8 (putative) -4.25471
ACOT9 acyl-CoA thioesterase 9 -3.70364
RNF167 ring finger protein 167 -3.07696
UFM1 ubiquitin-fold modifier 1 -3.04641
KIF14 kinesin family member 14 -2.98852
KRT14 keratin 14, type I -2.92254
DHRS7 dehydrogenase/reductase (SDR family) member 7 -2.59695
PFN1 profilin 1 -2.36035
PANK4 pantothenate kinase 4 -2.30389
SLC35A5 solute carrier family 35, member A5 -2.22274
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2 -2.01746