CRCGN016_MCF10A.TP53.M_24H:L16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,2-dichloropropane 99.3 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:L16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MNAT1 MNAT CDK-activating kinase assembly factor 1 4.68827
WIF1 WNT inhibitory factor 1 4.63356
STIMATE STIM activating enhancer 4.18422
KCTD5 potassium channel tetramerization domain containing 5 4.12988
E2F2 E2F transcription factor 2 4.11443
AXIN1 axin 1 3.8773
BZW2 basic leucine zipper and W2 domains 2 3.59886
MAP7 microtubule-associated protein 7 3.29361
SYNGAP1 synaptic Ras GTPase activating protein 1 2.82655
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 2.5336
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.50308
VGLL4 vestigial-like family member 4 2.45484
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.3273
MBOAT7 membrane bound O-acyltransferase domain containing 7 2.16217

decreased expression

Symbol Name Standardized Value
COG2 component of oligomeric golgi complex 2 -4.98181
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -4.52274
SLC35F2 solute carrier family 35, member F2 -4.2891
TRAPPC3 trafficking protein particle complex 3 -4.16211
NOSIP nitric oxide synthase interacting protein -2.3561
MRPS15 mitochondrial ribosomal protein S15 -2.35254
CASP3 caspase 3, apoptosis-related cysteine peptidase -2.19906
BPHL biphenyl hydrolase-like (serine hydrolase) -2.18549
EMP3 epithelial membrane protein 3 -2.0274