CRCGN016_MCF10A.TP53.M_24H:L17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,2-dichloropropane 33.1 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

12 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:L17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCNA1 cyclin A1 3.96813
ACAA1 acetyl-CoA acyltransferase 1 2.49659
C2CD2 C2 calcium-dependent domain containing 2 2.46864
KDM5D lysine (K)-specific demethylase 5D 2.42842
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.26153
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.15271

decreased expression

Symbol Name Standardized Value
RPIA ribose 5-phosphate isomerase A -3.42016
KIF14 kinesin family member 14 -3.22382
ISOC1 isochorismatase domain containing 1 -3.06416
VDAC1 voltage-dependent anion channel 1 -2.81711
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.42337
SMC1A structural maintenance of chromosomes 1A -2.03219