CRCGN016_MCF10A.TP53.M_24H:L20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description atrazine 33.32 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:L20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADO 2-aminoethanethiol (cysteamine) dioxygenase 4.81088
STK10 serine/threonine kinase 10 4.55348
MAMLD1 mastermind-like domain containing 1 4.13013
RPL39L ribosomal protein L39-like 3.26924
CCP110 centriolar coiled coil protein 110kDa 3.09967
KDM5D lysine (K)-specific demethylase 5D 3.08715
CHIC2 cysteine-rich hydrophobic domain 2 2.99062
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.75183
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.73643
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.46094
HBA1 hemoglobin, alpha 1 2.34469
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.15195
RAB21 RAB21, member RAS oncogene family 2.1517
PRR7 proline rich 7 (synaptic) 2.09846
PHC2 polyhomeotic homolog 2 (Drosophila) 2.03308

decreased expression

Symbol Name Standardized Value
NVL nuclear VCP-like -2.82683
KDM5C lysine (K)-specific demethylase 5C -2.6336
CDK4 cyclin-dependent kinase 4 -2.51536
GRWD1 glutamate-rich WD repeat containing 1 -2.36967
UFM1 ubiquitin-fold modifier 1 -2.31795
SMC1A structural maintenance of chromosomes 1A -2.13604
TKT transketolase -2.03548