CRCGN016_MCF10A.TP53.M_24H:L21 Gene Set
Genes
28 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:L21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
EVL
|
Enah/Vasp-like
|
3.75744
|
|
CASP10
|
caspase 10, apoptosis-related cysteine peptidase
|
3.12123
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
2.83301
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
2.79799
|
|
EDN1
|
endothelin 1
|
2.69753
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
2.4995
|
|
NFATC3
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
|
2.4206
|
|
KL
|
klotho
|
2.38289
|
|
LGMN
|
legumain
|
2.37692
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
2.28262
|
|
GIMAP4
|
GTPase, IMAP family member 4
|
2.27997
|
|
BMX
|
BMX non-receptor tyrosine kinase
|
2.25284
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.23841
|
|
MMP7
|
matrix metallopeptidase 7
|
2.15905
|
|
ACSM1
|
acyl-CoA synthetase medium-chain family member 1
|
2.15799
|
|
MERTK
|
MER proto-oncogene, tyrosine kinase
|
2.14949
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
2.14567
|
|
ZBP1
|
Z-DNA binding protein 1
|
2.11961
|
|
PDZK1IP1
|
PDZK1 interacting protein 1
|
2.11319
|
|
SLC17A1
|
solute carrier family 17 (organic anion transporter), member 1
|
2.08202
|
|
KIFC3
|
kinesin family member C3
|
2.03584
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ADI1
|
acireductone dioxygenase 1
|
-3.9994
|
|
ATF5
|
activating transcription factor 5
|
-3.86328
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.64227
|
|
TCTA
|
T-cell leukemia translocation altered
|
-2.74908
|
|
PFN1
|
profilin 1
|
-2.43367
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.19014
|
|
TEX10
|
testis expressed 10
|
-2.10959
|
