CRCGN016_MCF10A.TP53.M_24H:M01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description nitrofurantoin 99.3 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

479 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:M01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ZNF586 zinc finger protein 586 10.0
HMOX1 heme oxygenase 1 10.0
TXNRD1 thioredoxin reductase 1 9.56235
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 6.59565
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 6.54905
ASNS asparagine synthetase (glutamine-hydrolyzing) 6.2903
ZNF134 zinc finger protein 134 6.2779
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 5.64945
SNAP25 synaptosomal-associated protein, 25kDa 5.3505
GLRX glutaredoxin (thioltransferase) 5.30898
FKBP14 FK506 binding protein 14, 22 kDa 5.0328
COMP cartilage oligomeric matrix protein 5.0
CADM1 cell adhesion molecule 1 4.922
AARS1 alanyl-tRNA synthetase 1 4.84455
ZNF671 zinc finger protein 671 4.7907
ZNF551 zinc finger protein 551 4.7101
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 4.5134
AMDHD2 amidohydrolase domain containing 2 4.50645
LOC128125814 uncharacterized LOC128125814 4.48655
ZNF419 zinc finger protein 419 4.46542
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 4.3679
PSAT1 phosphoserine aminotransferase 1 4.2214
GARS1 glycyl-tRNA synthetase 1 4.21635
ZNF587B zinc finger protein 587B 4.0897
KDM5D lysine (K)-specific demethylase 5D 4.00845
ZIM3 zinc finger, imprinted 3 4.0002
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 3.96015
MCOLN1 mucolipin 1 3.9292
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 3.92655
ZNF544 zinc finger protein 544 3.89675
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 3.89505
ZNF304 zinc finger protein 304 3.88145
STMN2 stathmin 2 3.81442
SARS1 seryl-tRNA synthetase 1 3.81355
YARS1 tyrosyl-tRNA synthetase 1 3.71955
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 3.7142
ATF4 activating transcription factor 4 3.70435
CHN1 chimerin 1 3.6935
ZNF587 zinc finger protein 587 3.64285
ZNF136 zinc finger protein 136 3.635
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 3.62017
ZNF91 zinc finger protein 91 3.58745
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 3.55368
WIF1 WNT inhibitory factor 1 3.52715
ZNF135 zinc finger protein 135 3.52245
PHGDH phosphoglycerate dehydrogenase 3.49003
ZNF211 zinc finger protein 211 3.4564
RPH3A rabphilin 3A 3.4478
ZNF426 zinc finger protein 426 3.4228
TAGLN3 transgelin 3 3.4211
IL1B interleukin 1, beta 3.39087
TRIB3 tribbles pseudokinase 3 3.3571
UGDH UDP-glucose 6-dehydrogenase 3.33745
TARS1 threonyl-tRNA synthetase 1 3.28515
UPP1 uridine phosphorylase 1 3.27765
NSG2 neuronal vesicle trafficking associated 2 3.2441
SYN1 synapsin I 3.2396
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 3.2046
XPOT exportin, tRNA 3.158
PYCR1 pyrroline-5-carboxylate reductase 1 3.1449
USP9Y ubiquitin specific peptidase 9, Y-linked 3.1385
ZFP69B ZFP69 zinc finger protein B 3.10935
THAP4 THAP domain containing 4 3.0784
TMEM268 transmembrane protein 268 3.06785
RALYL RALY RNA binding protein-like 3.06535
CTSL cathepsin L 3.04795
ZNF430 zinc finger protein 430 3.0281
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 3.02535
ZNF548 zinc finger protein 548 3.0149
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 2.9846
BPI bactericidal/permeability-increasing protein 2.94055
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.93992
IL1A interleukin 1, alpha 2.9257
AURKC aurora kinase C 2.91245
ZNF761 zinc finger protein 761 2.9054
SNCB synuclein, beta 2.8805
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.87965
DUSP5 dual specificity phosphatase 5 2.86375
FERRY3 FERRY endosomal RAB5 effector complex subunit 3 2.84085
SYT1 synaptotagmin I 2.8212
TRH thyrotropin-releasing hormone 2.8198
RUNDC3A RUN domain containing 3A 2.8164
KLHL7 kelch-like family member 7 2.8123
ZNF93 zinc finger protein 93 2.80053
ALAS1 5'-aminolevulinate synthase 1 2.79765
ACTL6B actin-like 6B 2.79415
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.7858
DDA1 DET1 and DDB1 associated 1 2.77945
USP3 ubiquitin specific peptidase 3 2.771
GOLT1A golgi transport 1A 2.7527
NEFL neurofilament, light polypeptide 2.7475
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 2.74412
GTPBP2 GTP binding protein 2 2.73255
BCL2L13 BCL2-like 13 (apoptosis facilitator) 2.70985
NECAP1 NECAP endocytosis associated 1 2.69825
PCDHB13 protocadherin beta 13 2.6969
ODR4 odr-4 GPCR localization factor homolog 2.6764
NEFM neurofilament, medium polypeptide 2.67445
REXO5 RNA exonuclease 5 2.67335
CDPF1 cysteine-rich, DPF motif domain containing 1 2.6669
CHAMP1 chromosome alignment maintaining phosphoprotein 1 2.66
QPCT glutaminyl-peptide cyclotransferase 2.65735
SYP synaptophysin 2.65325
BAMBI BMP and activin membrane-bound inhibitor 2.64725
ZNF415 zinc finger protein 415 2.61855
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 2.6151
MARS1 methionyl-tRNA synthetase 1 2.60487
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 2.60015
NHLH2 nescient helix loop helix 2 2.59917
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 2.58235
HSPA13 heat shock protein 70kDa family, member 13 2.57483
SLURP1 secreted LY6/PLAUR domain containing 1 2.5625
EFS embryonal Fyn-associated substrate 2.56015
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 2.5599
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) 2.55525
GBX2 gastrulation brain homeobox 2 2.5533
ZFAND1 zinc finger, AN1-type domain 1 2.55235
ZNF667 zinc finger protein 667 2.5508
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 2.5103
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) 2.50213
ZIC3 Zic family member 3 2.4998
MAPRE3 microtubule-associated protein, RP/EB family, member 3 2.49953
CDK7 cyclin-dependent kinase 7 2.49895
HBA1 hemoglobin, alpha 1 2.49825
EMC7 ER membrane protein complex subunit 7 2.49765
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.49685
WARS1 tryptophanyl-tRNA synthetase 1 2.49613
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 2.4948
RGS11 regulator of G-protein signaling 11 2.49293
CRCT1 cysteine-rich C-terminal 1 2.47695
CNTN1 contactin 1 2.476
MNS1 meiosis-specific nuclear structural 1 2.468
S100A12 S100 calcium binding protein A12 2.4665
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 2.46565
ZNF350 zinc finger protein 350 2.4647
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 2.4577
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.45425
WNT5A wingless-type MMTV integration site family, member 5A 2.44283
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.43645
TMEM140 transmembrane protein 140 2.43325
ANTXR1 anthrax toxin receptor 1 2.42225
ZNF787 zinc finger protein 787 2.4155
PCSK1 proprotein convertase subtilisin/kexin type 1 2.4117
ZNF253 zinc finger protein 253 2.4086
STEAP1B STEAP family member 1B 2.3967
SNAP91 synaptosomal-associated protein, 91kDa 2.3933
RAB30 RAB30, member RAS oncogene family 2.39055
ZNF273 zinc finger protein 273 2.3877
ZNF814 zinc finger protein 814 2.38232
BHMT2 betaine--homocysteine S-methyltransferase 2 2.3775
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 2.37725
CBLN1 cerebellin 1 precursor 2.37655
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 2.3655
PENK proenkephalin 2.36395
TUBB4A tubulin, beta 4A class IVa 2.3638
RBP4 retinol binding protein 4, plasma 2.3548
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 2.3443
CCN4 cellular communication network factor 4 2.34218
MATN3 matrilin 3 2.3416
CRYBB2 crystallin, beta B2 2.339
MAG myelin associated glycoprotein 2.33885
ECSIT ECSIT signalling integrator 2.33695
INHBA inhibin, beta A 2.33645
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 2.3344
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 2.3314
BCL2L2 BCL2-like 2 2.32755
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 2.32655
TGM3 transglutaminase 3 2.326
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 2.31905
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 2.31795
ZNF660-ZNF197 ZNF660-ZNF197 readthrough 2.3164
ZKSCAN7 zinc finger with KRAB and SCAN domains 7 2.31275
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 2.31205
FXYD7 FXYD domain containing ion transport regulator 7 2.30915
FGF13 fibroblast growth factor 13 2.3043
BACE2 beta-site APP-cleaving enzyme 2 2.2994
ELOVL4 ELOVL fatty acid elongase 4 2.29685
BIRC7 baculoviral IAP repeat containing 7 2.2941
OXR1 oxidation resistance 1 2.293
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 2.29126
VSNL1 visinin-like 1 2.28915
CBARP CACN subunit beta associated regulatory protein 2.2888
QTRT1 queuine tRNA-ribosyltransferase 1 2.28695
DUSP4 dual specificity phosphatase 4 2.28125
DCC DCC netrin 1 receptor 2.2784
OMD osteomodulin 2.27708
H1-1 H1.1 linker histone, cluster member 2.2732
PGAP4 post-GPI attachment to proteins GalNAc transferase 4 2.2718
GINS4 GINS complex subunit 4 (Sld5 homolog) 2.2696
MAPK12 mitogen-activated protein kinase 12 2.2648
PCSK2 proprotein convertase subtilisin/kexin type 2 2.26143
SH3GL2 SH3-domain GRB2-like 2 2.25995
MSRA methionine sulfoxide reductase A 2.25905
TBC1D2 TBC1 domain family, member 2 2.254
PLAU plasminogen activator, urokinase 2.25225
CEP15 centrosomal protein 15 2.2518
OSGIN1 oxidative stress induced growth inhibitor 1 2.2467
SCFD1 sec1 family domain containing 1 2.2408
GLRA2 glycine receptor, alpha 2 2.23585
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 2.23488
ACVR1 activin A receptor, type I 2.23215
WASF3 WAS protein family, member 3 2.2321
GHITM growth hormone inducible transmembrane protein 2.23085
AMBN ameloblastin (enamel matrix protein) 2.23
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 2.22855
NIT1 nitrilase 1 2.22685
DAZ2 deleted in azoospermia 2 2.22045
PTPRN protein tyrosine phosphatase, receptor type, N 2.2171
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 2.21705
PGLYRP1 peptidoglycan recognition protein 1 2.2151
LAPTM4A lysosomal protein transmembrane 4 alpha 2.2148
SDC1 syndecan 1 2.21362
ONECUT2 one cut homeobox 2 2.2056
DEFA3 defensin, alpha 3, neutrophil-specific 2.20505
PCDHB12 protocadherin beta 12 2.2015
IQCB1 IQ motif containing B1 2.1986
CD19 CD19 molecule 2.1964
TES testin LIM domain protein 2.19578
HAX1 HCLS1 associated protein X-1 2.1951
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 2.19478
SLCO2A1 solute carrier organic anion transporter family, member 2A1 2.19445
CHIC2 cysteine-rich hydrophobic domain 2 2.1869
PPCDC phosphopantothenoylcysteine decarboxylase 2.18635
ZSCAN18 zinc finger and SCAN domain containing 18 2.18493
BAX BCL2-associated X protein 2.1829
ZNF197 zinc finger protein 197 2.182
GPR37L1 G protein-coupled receptor 37 like 1 2.1805
SHB Src homology 2 domain containing adaptor protein B 2.17948
GLRX2 glutaredoxin 2 2.1762
LIAS lipoic acid synthetase 2.1761
CAVIN3 caveolae associated protein 3 2.17335
MOSPD1 motile sperm domain containing 1 2.1711
ZNF215 zinc finger protein 215 2.17035
INHBE inhibin, beta E 2.168
OSBPL10 oxysterol binding protein-like 10 2.16545
SYNGR1 synaptogyrin 1 2.16457
NALF1 NALCN channel auxiliary factor 1 2.15625
SP140 SP140 nuclear body protein 2.1551
ANGPT1 angiopoietin 1 2.15403
SLC16A6 solute carrier family 16, member 6 2.1505
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 2.1495
ZXDA zinc finger, X-linked, duplicated A 2.1457
IL36A interleukin 36, alpha 2.14
SQSTM1 sequestosome 1 2.13965
EBF2 early B-cell factor 2 2.1333
GRIA2 glutamate receptor, ionotropic, AMPA 2 2.1266
ZNF14 zinc finger protein 14 2.12585
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 2.12475
RRAGC Ras-related GTP binding C 2.1239
RNF13 ring finger protein 13 2.12387
ENDOU endonuclease, polyU-specific 2.1232
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.12287
GSTZ1 glutathione S-transferase zeta 1 2.12205
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.1208
FLG filaggrin 2.1198
DKK4 dickkopf WNT signaling pathway inhibitor 4 2.1194
BZW2 basic leucine zipper and W2 domains 2 2.1192
BCAS4 breast carcinoma amplified sequence 4 2.11625
LOC122539214 Zinc finger protein LOC122539214 2.115
LPAR1 lysophosphatidic acid receptor 1 2.11462
ZNF562 zinc finger protein 562 2.11325
JOSD1 Josephin domain containing 1 2.1103
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.1086
RBP3 retinol binding protein 3, interstitial 2.1056
KCNK3 potassium channel, two pore domain subfamily K, member 3 2.10445
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 2.10405
VAMP4 vesicle-associated membrane protein 4 2.1022
PREPL prolyl endopeptidase-like 2.10143
TMX2 thioredoxin-related transmembrane protein 2 2.10035
ZC3H15 zinc finger CCCH-type containing 15 2.09812
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 2.09748
GREB1L growth regulation by estrogen in breast cancer-like 2.0964
GBA1 glucosylceramidase beta 1 2.0946
NPTX1 neuronal pentraxin I 2.0946
TMEM35A transmembrane protein 35A 2.09365
ZNF44 zinc finger protein 44 2.0922
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 2.0919
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 2.09175
KLHL12 kelch-like family member 12 2.09025
ST18 suppression of tumorigenicity 18, zinc finger 2.0895
CST1 cystatin SN 2.0894
MCTS1 malignant T cell amplified sequence 1 2.0893
MEF2B myocyte enhancer factor 2B 2.08885
TALDO1 transaldolase 1 2.087
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 2.0857
HAND1 heart and neural crest derivatives expressed 1 2.08005
NDRG4 NDRG family member 4 2.0712
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 2.06087
PRSS58 protease, serine, 58 2.05985
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 2.05965
MMP11 matrix metallopeptidase 11 2.05805
TTC17 tetratricopeptide repeat domain 17 2.05635
FGD1 FYVE, RhoGEF and PH domain containing 1 2.0521
CDC37 cell division cycle 37 2.0512
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11 2.04895
PELO pelota homolog (Drosophila) 2.04625
ZSCAN2 zinc finger and SCAN domain containing 2 2.0443
RGL4 ral guanine nucleotide dissociation stimulator-like 4 2.04235
PKD2L1 polycystic kidney disease 2-like 1 2.04215
IER3 immediate early response 3 2.04085
HPCAL1 hippocalcin-like 1 2.04017
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 2.03685
EPRS1 glutamyl-prolyl-tRNA synthetase 1 2.03513
NLGN4Y neuroligin 4, Y-linked 2.0345
PLPPR4 phospholipid phosphatase related 4 2.0328
GPC1 glypican 1 2.03198
ZNF682 zinc finger protein 682 2.03195
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta 2.02935
LOC128125822 uncharacterized LOC128125822 2.0273
BRINP1 bone morphogenetic protein/retinoic acid inducible neural-specific 1 2.0243
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 2.02205
IL36RN interleukin 36 receptor antagonist 2.0211
PID1 phosphotyrosine interaction domain containing 1 2.01955
EPHB6 EPH receptor B6 2.01615
EPYC epiphycan 2.0158
SH3PXD2A SH3 and PX domains 2A 2.01402
CCDC15 coiled-coil domain containing 15 2.0135
CCNA1 cyclin A1 2.0129
ZFY zinc finger protein, Y-linked 2.0123
NAMPT nicotinamide phosphoribosyltransferase 2.01108
RABGGTB Rab geranylgeranyltransferase, beta subunit 2.00605
MCC mutated in colorectal cancers 2.00455
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 2.00397
ELAVL2 ELAV like neuron-specific RNA binding protein 2 2.0024

decreased expression

Symbol Name Standardized Value
KIF14 kinesin family member 14 -7.02825
UBE2C ubiquitin-conjugating enzyme E2C -6.4693
CCNB1 cyclin B1 -6.25075
CDC20 cell division cycle 20 -6.1902
ANKRD10 ankyrin repeat domain 10 -5.82695
HMG20B high mobility group 20B -5.8265
KIF20A kinesin family member 20A -5.3484
BLCAP bladder cancer associated protein -5.3105
PLK1 polo-like kinase 1 -5.20835
PCNA proliferating cell nuclear antigen -5.0
GRWD1 glutamate-rich WD repeat containing 1 -4.3849
AURKA aurora kinase A -3.93575
DDB2 damage-specific DNA binding protein 2, 48kDa -3.8838
PSRC1 proline/serine-rich coiled-coil 1 -3.84075
SMC1A structural maintenance of chromosomes 1A -3.75643
MATN2 matrilin 2 -3.4171
TMEM50A transmembrane protein 50A -3.3701
HMMR hyaluronan-mediated motility receptor (RHAMM) -3.32748
THAP11 THAP domain containing 11 -3.3228
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 -3.30145
TPX2 TPX2, microtubule-associated -3.2872
CCNF cyclin F -3.1877
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.18598
CCNB2 cyclin B2 -3.1387
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 -3.13155
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -3.1311
HMGB2 high mobility group box 2 -3.0926
STMN1 stathmin 1 -3.05075
NEK4 NIMA-related kinase 4 -3.01735
KIF4A kinesin family member 4A -2.96285
GOLGA8N golgin A8 family, member N -2.9418
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.93785
BIRC5 baculoviral IAP repeat containing 5 -2.92607
RHBDF2 rhomboid 5 homolog 2 (Drosophila) -2.8804
AP5S1 adaptor-related protein complex 5, sigma 1 subunit -2.8615
CIDEB cell death-inducing DFFA-like effector b -2.84665
SNRPG small nuclear ribonucleoprotein polypeptide G -2.84325
IGFBP7 insulin-like growth factor binding protein 7 -2.83617
USP9X ubiquitin specific peptidase 9, X-linked -2.80508
RALY RALY heterogeneous nuclear ribonucleoprotein -2.74765
TOP2A topoisomerase (DNA) II alpha 170kDa -2.7153
DAAM1 dishevelled associated activator of morphogenesis 1 -2.6681
CDK1 cyclin-dependent kinase 1 -2.66518
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -2.65077
PRAF2 PRA1 domain family, member 2 -2.6253
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.5851
KIF15 kinesin family member 15 -2.58175
CKAP5 cytoskeleton associated protein 5 -2.55395
F8 coagulation factor VIII, procoagulant component -2.55085
KDM6A lysine (K)-specific demethylase 6A -2.54263
SEC23B Sec23 homolog B (S. cerevisiae) -2.53605
CDC25B cell division cycle 25B -2.5287
GLB1 galactosidase, beta 1 -2.5262
CRNKL1 crooked neck pre-mRNA splicing factor 1 -2.51915
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 -2.50455
HDAC1 histone deacetylase 1 -2.4979
PTTG1 pituitary tumor-transforming 1 -2.47245
HIPK3 homeodomain interacting protein kinase 3 -2.47115
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) -2.46515
ACOT8 acyl-CoA thioesterase 8 -2.46315
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa -2.4449
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 -2.4421
ATG2B autophagy related 2B -2.43655
COG4 component of oligomeric golgi complex 4 -2.4317
MYOM2 myomesin 2 -2.41605
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -2.4134
GFUS GDP-L-fucose synthase -2.4089
TMPO thymopoietin -2.39568
ZFHX3 zinc finger homeobox 3 -2.3683
AGGF1 angiogenic factor with G patch and FHA domains 1 -2.36462
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 -2.3626
NUSAP1 nucleolar and spindle associated protein 1 -2.36255
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) -2.35435
BAG3 BCL2-associated athanogene 3 -2.3513
FASTKD5 FAST kinase domains 5 -2.3505
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A -2.34113
METRN meteorin, glial cell differentiation regulator -2.33855
WDR37 WD repeat domain 37 -2.3267
INCENP inner centromere protein antigens 135/155kDa -2.3156
BTN3A2 butyrophilin, subfamily 3, member A2 -2.29727
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -2.2941
UBOX5 U-box domain containing 5 -2.27857
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 -2.27245
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -2.26965
SCAF8 SR-related CTD-associated factor 8 -2.2559
KARS1 lysyl-tRNA synthetase 1 -2.2548
YBX1 Y box binding protein 1 -2.25385
MAN2B2 mannosidase, alpha, class 2B, member 2 -2.25015
JAG2 jagged 2 -2.24375
PPIH peptidylprolyl isomerase H (cyclophilin H) -2.24285
CKS2 CDC28 protein kinase regulatory subunit 2 -2.2228
HOXA5 homeobox A5 -2.22155
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.21835
PGAM4 phosphoglycerate mutase family member 4 -2.20745
GOLGA8F golgin A8 family, member F -2.2017
NUP133 nucleoporin 133kDa -2.20145
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 -2.19075
CKAP2 cytoskeleton associated protein 2 -2.1866
LIPG lipase, endothelial -2.18445
KIFC1 kinesin family member C1 -2.17905
SPAG5 sperm associated antigen 5 -2.17335
ZNF629 zinc finger protein 629 -2.17305
CX3CR1 chemokine (C-X3-C motif) receptor 1 -2.16775
TBC1D4 TBC1 domain family, member 4 -2.1661
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 -2.1629
TMEM231 transmembrane protein 231 -2.1583
CCL5 chemokine (C-C motif) ligand 5 -2.15685
RACGAP1 Rac GTPase activating protein 1 -2.15445
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.15307
NCOA6 nuclear receptor coactivator 6 -2.15105
CENPA centromere protein A -2.14757
RYR1 ryanodine receptor 1 (skeletal) -2.1469
SERF1A small EDRK-rich factor 1A (telomeric) -2.13735
H2AX H2A.X variant histone -2.13435
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 -2.13
MCM9 minichromosome maintenance complex component 9 -2.1248
HEXIM1 hexamethylene bis-acetamide inducible 1 -2.12302
FUCA1 fucosidase, alpha-L- 1, tissue -2.12285
PUDP pseudouridine 5'-phosphatase -2.1219
CEP55 centrosomal protein 55kDa -2.11995
ADGRE5 adhesion G protein-coupled receptor E5 -2.11885
MICB MHC class I polypeptide-related sequence B -2.1177
PIMREG PICALM interacting mitotic regulator -2.1094
TCEAL4 transcription elongation factor A (SII)-like 4 -2.10935
CUTC cutC copper transporter -2.10535
TDP1 tyrosyl-DNA phosphodiesterase 1 -2.0869
TMEM168 transmembrane protein 168 -2.0854
NT5DC2 5'-nucleotidase domain containing 2 -2.0821
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.08205
CD320 CD320 molecule -2.0815
ASF1B anti-silencing function 1B histone chaperone -2.08115
TASOR transcription activation suppressor -2.08113
HSPA8 heat shock 70kDa protein 8 -2.0754
NBPF3 neuroblastoma breakpoint family, member 3 -2.0695
SNX5 sorting nexin 5 -2.0687
CSNK1G2 casein kinase 1, gamma 2 -2.06815
SCPEP1 serine carboxypeptidase 1 -2.0654
SELENOW selenoprotein W -2.06315
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.061
RBL2 retinoblastoma-like 2 -2.0606
FAM50B family with sequence similarity 50, member B -2.05865
DENND2D DENN/MADD domain containing 2D -2.0529
DPYD dihydropyrimidine dehydrogenase -2.05045
LONP2 lon peptidase 2, peroxisomal -2.03985
PRPF8 pre-mRNA processing factor 8 -2.0372
SNX15 sorting nexin 15 -2.0341
RIC8B RIC8 guanine nucleotide exchange factor B -2.03405
CTR9 CTR9, Paf1/RNA polymerase II complex component -2.03135
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.0311
FLNA filamin A, alpha -2.01753
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 -2.01675
MVB12B multivesicular body subunit 12B -2.01633
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.01555
MAP2K2 mitogen-activated protein kinase kinase 2 -2.01503
TBC1D10C TBC1 domain family, member 10C -2.0118