CRCGN016_MCF10A.TP53.M_24H:M02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description nitrofurantoin 33.1 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:M02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
WFS1 Wolfram syndrome 1 (wolframin) 4.58415
GATA3 GATA binding protein 3 4.39983
CHMP6 charged multivesicular body protein 6 4.27722
SNAP25 synaptosomal-associated protein, 25kDa 4.25428
LAGE3 L antigen family, member 3 4.21641
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 3.79872
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 2.7623
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.51091
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.28782
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2.22757

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -4.32556
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -4.23312
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -3.8771
CIAPIN1 cytokine induced apoptosis inhibitor 1 -3.35235
NT5DC2 5'-nucleotidase domain containing 2 -3.19045
TES testin LIM domain protein -3.04417
CDC45 cell division cycle 45 -2.72227
GRWD1 glutamate-rich WD repeat containing 1 -2.44444