CRCGN016_MCF10A.TP53.M_24H:M03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description nitrofurantoin 11.03 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

37 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:M03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCP110 centriolar coiled coil protein 110kDa 5.30421
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 5.28664
MYLK myosin light chain kinase 4.49031
SPAG4 sperm associated antigen 4 4.03061
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 3.94609
MINDY1 MINDY lysine 48 deubiquitinase 1 3.21587
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 2.93868
ACBD3 acyl-CoA binding domain containing 3 2.73221
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 2.5835
FIP1L1 factor interacting with PAPOLA and CPSF1 2.55181
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.41526
MMP1 matrix metallopeptidase 1 2.39943
RXYLT1 ribitol xylosyltransferase 1 2.3059
PLS1 plastin 1 2.23165
TIPIN TIMELESS interacting protein 2.16847
GET1 guided entry of tail-anchored proteins factor 1 2.06551

decreased expression

Symbol Name Standardized Value
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -4.55516
KIF20A kinesin family member 20A -4.15809
RPS5 ribosomal protein S5 -4.14314
RPL18 ribosomal protein L18 -2.76349
KDM3A lysine (K)-specific demethylase 3A -2.67167
RPL29 ribosomal protein L29 -2.50113
ATP11B ATPase, class VI, type 11B -2.39158
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -2.30983
RPL6 ribosomal protein L6 -2.27299
STIMATE STIM activating enhancer -2.25484
NOP53 NOP53 ribosome biogenesis factor -2.2343
RPLP2 ribosomal protein, large, P2 -2.21175
STXBP2 syntaxin binding protein 2 -2.12162
EXD3 exonuclease 3'-5' domain containing 3 -2.09813
TOR1A torsin family 1, member A (torsin A) -2.08816
DGCR2 DiGeorge syndrome critical region gene 2 -2.08625
RLN1 relaxin 1 -2.06691
TP53BP2 tumor protein p53 binding protein 2 -2.02135
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific -2.01455
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -2.01296
HAMP hepcidin antimicrobial peptide -2.01097