CRCGN016_MCF10A.TP53.M_24H:M05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description bis(chloromethyl) ether 33.43 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:M05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.64307
STIMATE STIM activating enhancer 3.60774
CXCL2 chemokine (C-X-C motif) ligand 2 3.57701
CHN1 chimerin 1 3.08218
SPAG4 sperm associated antigen 4 2.85541
GADD45A growth arrest and DNA-damage-inducible, alpha 2.66221
FZD1 frizzled class receptor 1 2.6507
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.62022

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -4.48339
MPC2 mitochondrial pyruvate carrier 2 -4.21342
GRN granulin -3.36767
NLRP4 NLR family, pyrin domain containing 4 -3.21425
EXOSC4 exosome component 4 -2.48579
STXBP2 syntaxin binding protein 2 -2.374
NUSAP1 nucleolar and spindle associated protein 1 -2.25855
KCNK1 potassium channel, two pore domain subfamily K, member 1 -2.25467
TRAPPC6A trafficking protein particle complex 6A -2.02617