CRCGN016_MCF10A.TP53.M_24H:M06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description bis(chloromethyl) ether 11.14 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:M06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 5.12227
C2CD2 C2 calcium-dependent domain containing 2 4.95727
CARMIL1 capping protein regulator and myosin 1 linker 1 4.43744
BAMBI BMP and activin membrane-bound inhibitor 3.21059
DENND2D DENN/MADD domain containing 2D 3.20198
CASP7 caspase 7, apoptosis-related cysteine peptidase 3.10822
TXNL4B thioredoxin-like 4B 2.39464
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.21629

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -4.75537
COTL1 coactosin-like F-actin binding protein 1 -4.0176
LAP3 leucine aminopeptidase 3 -3.77086
PRCP prolylcarboxypeptidase (angiotensinase C) -3.36002
KRT14 keratin 14, type I -3.3179
MT1X metallothionein 1X -2.76866
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.08464