CRCGN016_MCF10A.TP53.M_24H:M08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description beta testosterone 33.1 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

39 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:M08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GRB10 growth factor receptor-bound protein 10 5.1018
HBA1 hemoglobin, alpha 1 3.66998
SPAG4 sperm associated antigen 4 3.65496
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 3.64194
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.62121
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 3.53782
TBPL1 TBP-like 1 3.20561
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.83981
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.60063
FSD1 fibronectin type III and SPRY domain containing 1 2.51353
RAB21 RAB21, member RAS oncogene family 2.43853
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.28655
KDM5D lysine (K)-specific demethylase 5D 2.27723
PRKX protein kinase, X-linked 2.27073
MCUR1 mitochondrial calcium uniporter regulator 1 2.25843
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 2.08229
INTS9 integrator complex subunit 9 2.05687
OXCT1 3-oxoacid CoA transferase 1 2.00194

decreased expression

Symbol Name Standardized Value
TEX10 testis expressed 10 -5.28002
CORO1A coronin, actin binding protein, 1A -4.43166
CAB39 calcium binding protein 39 -3.50712
UBE3C ubiquitin protein ligase E3C -3.41273
CRK v-crk avian sarcoma virus CT10 oncogene homolog -3.19359
GRN granulin -2.96884
ETFB electron-transfer-flavoprotein, beta polypeptide -2.66802
PMM2 phosphomannomutase 2 -2.48321
CD82 CD82 molecule -2.36385
AMDHD2 amidohydrolase domain containing 2 -2.33938
PRR15L proline rich 15-like -2.33116
ZNF430 zinc finger protein 430 -2.20501
SMC1A structural maintenance of chromosomes 1A -2.18752
BORCS6 BLOC-1 related complex subunit 6 -2.14118
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.13493
TMBIM1 transmembrane BAX inhibitor motif containing 1 -2.12533
TSC22D3 TSC22 domain family, member 3 -2.11269
MSMO1 methylsterol monooxygenase 1 -2.0688
GPR88 G protein-coupled receptor 88 -2.0652
ZNF189 zinc finger protein 189 -2.05978
ANXA4 annexin A4 -2.00672