CRCGN016_MCF10A.TP53.M_24H:M10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dibromomannitol 99.8 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:M10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 5.8423
WIF1 WNT inhibitory factor 1 3.70742
GATA3 GATA binding protein 3 3.30247
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.91492
HBA1 hemoglobin, alpha 1 2.7937
COMP cartilage oligomeric matrix protein 2.5871
NGRN neugrin, neurite outgrowth associated 2.47324
MDN1 MDN1, midasin homolog (yeast) 2.38609
UGDH UDP-glucose 6-dehydrogenase 2.27965
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.10196
FLNA filamin A, alpha 2.07446

decreased expression

Symbol Name Standardized Value
DYNLT3 dynein, light chain, Tctex-type 3 -5.32442
COG2 component of oligomeric golgi complex 2 -4.92087
PMM2 phosphomannomutase 2 -4.9162
TCTA T-cell leukemia translocation altered -4.66878
TCEAL4 transcription elongation factor A (SII)-like 4 -4.56153
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -4.15306
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.38304
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -3.14131
BAD BCL2-associated agonist of cell death -2.30022
HEATR6 HEAT repeat containing 6 -2.22809
TLK2 tousled-like kinase 2 -2.05559