CRCGN016_MCF10A.TP53.M_24H:M11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dibromomannitol 33.27 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:M11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCP110 centriolar coiled coil protein 110kDa 4.66489
KLHL21 kelch-like family member 21 3.48155
SNX11 sorting nexin 11 3.36238
KIF5C kinesin family member 5C 3.24786
IGHMBP2 immunoglobulin mu binding protein 2 2.95715
TBPL1 TBP-like 1 2.76256
CNRIP1 cannabinoid receptor interacting protein 1 2.72346
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.53064
ACAA1 acetyl-CoA acyltransferase 1 2.41986
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 2.05262

decreased expression

Symbol Name Standardized Value
CCNB1 cyclin B1 -3.55256
MRPS2 mitochondrial ribosomal protein S2 -3.45134
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -3.28621
PAEP progestagen-associated endometrial protein -2.99728
NGRN neugrin, neurite outgrowth associated -2.66634
SEC16A SEC16 homolog A (S. cerevisiae) -2.64079
PPP1R26 protein phosphatase 1, regulatory subunit 26 -2.51503
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.47642
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -2.39777
CDX2 caudal type homeobox 2 -2.18768
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.18707
GRN granulin -2.0496