CRCGN016_MCF10A.TP53.M_24H:M13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzo(b)fluoranthene 98.8 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:M13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CNRIP1 cannabinoid receptor interacting protein 1 3.86901
ABHD6 abhydrolase domain containing 6 3.46729
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 3.30059
SMIM40 small integral membrane protein 40 2.41586
BIRC2 baculoviral IAP repeat containing 2 2.35953
HBB hemoglobin, beta 2.311
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 2.25381
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.21082
CRELD2 cysteine-rich with EGF-like domains 2 2.17899

decreased expression

Symbol Name Standardized Value
ADI1 acireductone dioxygenase 1 -4.83699
CTNND1 catenin (cadherin-associated protein), delta 1 -4.00949
SLC35F2 solute carrier family 35, member F2 -3.87334
PGAM4 phosphoglycerate mutase family member 4 -3.63308
RNF167 ring finger protein 167 -3.6199
CAPN2 calpain 2, (m/II) large subunit -2.98616
GRWD1 glutamate-rich WD repeat containing 1 -2.27011
CLDN6 claudin 6 -2.0395