CRCGN016_MCF10A.TP53.M_24H:M15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzo(b)fluoranthene 10.98 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:M15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ZNF586 zinc finger protein 586 4.25179
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.6934
COMP cartilage oligomeric matrix protein 3.4899
BTK Bruton agammaglobulinemia tyrosine kinase 3.4411
GLOD4 glyoxalase domain containing 4 3.40271
ZNF134 zinc finger protein 134 3.28359
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 3.18249
LAGE3 L antigen family, member 3 2.96136
CNRIP1 cannabinoid receptor interacting protein 1 2.57328
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.55138
ZNF551 zinc finger protein 551 2.47885
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.35599
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.13755
TXNL4B thioredoxin-like 4B 2.05272
MSRA methionine sulfoxide reductase A 2.00466

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -6.78696
PCNA proliferating cell nuclear antigen -4.90788
C2CD5 C2 calcium-dependent domain containing 5 -3.86327
TM9SF2 transmembrane 9 superfamily member 2 -3.61419
KRT14 keratin 14, type I -3.35224
DHRS7 dehydrogenase/reductase (SDR family) member 7 -3.30156
CANT1 calcium activated nucleotidase 1 -3.12812
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -3.10062
PIH1D1 PIH1 domain containing 1 -2.42537
TUBA4A tubulin, alpha 4a -2.42061
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.27787
NRIP1 nuclear receptor interacting protein 1 -2.24834
ERC2 ELKS/RAB6-interacting/CAST family member 2 -2.22477
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.18525
CACTIN cactin, spliceosome C complex subunit -2.06029
SMC1A structural maintenance of chromosomes 1A -2.05997