CRCGN016_MCF10A.TP53.M_24H:M16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description chlorphenamine 99.8 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:M16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 3.67676
DENND2D DENN/MADD domain containing 2D 3.11949
TBX2 T-box 2 2.69152
HMOX1 heme oxygenase 1 2.58697
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.53897
ABHD4 abhydrolase domain containing 4 2.42568
TBPL1 TBP-like 1 2.42418
STAP2 signal transducing adaptor family member 2 2.34796
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 2.26281
ALDOC aldolase C, fructose-bisphosphate 2.10429
BZW2 basic leucine zipper and W2 domains 2 2.05672

decreased expression

Symbol Name Standardized Value
KIF14 kinesin family member 14 -3.21998
NUSAP1 nucleolar and spindle associated protein 1 -2.98234
DYNLT3 dynein, light chain, Tctex-type 3 -2.92698
TNIP1 TNFAIP3 interacting protein 1 -2.81289
BLCAP bladder cancer associated protein -2.38515