CRCGN016_MCF10A.TP53.M_24H:M17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description chlorphenamine 33.27 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

29 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:M17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 6.58971
ADGRE5 adhesion G protein-coupled receptor E5 6.58264
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.53765
SSBP2 single-stranded DNA binding protein 2 3.34423
CHEK1 checkpoint kinase 1 3.2705
GET1 guided entry of tail-anchored proteins factor 1 3.23929
KCTD5 potassium channel tetramerization domain containing 5 2.90383
GRB10 growth factor receptor-bound protein 10 2.85342
MEF2C myocyte enhancer factor 2C 2.84117
LOXL1 lysyl oxidase-like 1 2.79289
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2.55869
H2BC21 H2B clustered histone 21 2.53945
STAP2 signal transducing adaptor family member 2 2.51208
ANO10 anoctamin 10 2.32208
RFC5 replication factor C (activator 1) 5, 36.5kDa 2.17407
KDM5A lysine (K)-specific demethylase 5A 2.10791
SOX2 SRY (sex determining region Y)-box 2 2.06192
BAMBI BMP and activin membrane-bound inhibitor 2.04265

decreased expression

Symbol Name Standardized Value
BAG3 BCL2-associated athanogene 3 -3.54839
VAT1 vesicle amine transport 1 -3.35348
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.26592
HMG20B high mobility group 20B -2.99159
CTNND1 catenin (cadherin-associated protein), delta 1 -2.98748
BASP1 brain abundant, membrane attached signal protein 1 -2.57629
PSRC1 proline/serine-rich coiled-coil 1 -2.43282
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.42083
PCCB propionyl CoA carboxylase, beta polypeptide -2.23993
KRT14 keratin 14, type I -2.2007
CD81 CD81 molecule -2.16285