CRCGN016_MCF10A.TP53.M_24H:M20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ITE 34.23 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

33 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:M20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 4.59054
ACAA1 acetyl-CoA acyltransferase 1 3.09796
CNRIP1 cannabinoid receptor interacting protein 1 2.52014
CXCR4 chemokine (C-X-C motif) receptor 4 2.45606
WIF1 WNT inhibitory factor 1 2.40965
BAX BCL2-associated X protein 2.29676
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.27073
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.17555
EXOC2 exocyst complex component 2 2.15554
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.15391
RFWD3 ring finger and WD repeat domain 3 2.02901
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.00524

decreased expression

Symbol Name Standardized Value
OXA1L oxidase (cytochrome c) assembly 1-like -4.68923
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -4.18959
BLCAP bladder cancer associated protein -3.11453
IGBP1 immunoglobulin (CD79A) binding protein 1 -2.97685
GADD45B growth arrest and DNA-damage-inducible, beta -2.58845
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.53246
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 -2.52138
TRAPPC3 trafficking protein particle complex 3 -2.50763
GMPR2 guanosine monophosphate reductase 2 -2.36717
BASP1 brain abundant, membrane attached signal protein 1 -2.35607
SOAT2 sterol O-acyltransferase 2 -2.31703
ARID4A AT rich interactive domain 4A (RBP1-like) -2.27379
ATP11B ATPase, class VI, type 11B -2.26969
KDM3A lysine (K)-specific demethylase 3A -2.26685
PCNA proliferating cell nuclear antigen -2.192
TKT transketolase -2.17201
CSRP1 cysteine and glycine-rich protein 1 -2.10902
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) -2.10172
NCAPD2 non-SMC condensin I complex, subunit D2 -2.08593
AP5M1 adaptor-related protein complex 5, mu 1 subunit -2.05226
DGKD diacylglycerol kinase, delta 130kDa -2.00782