CRCGN016_MCF10A.TP53.M_24H:M24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dimetridazole 10.93 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:M24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RPL39L ribosomal protein L39-like 4.87798
SNAP25 synaptosomal-associated protein, 25kDa 4.59935
CDCA4 cell division cycle associated 4 3.99079
RAB31 RAB31, member RAS oncogene family 3.69467
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.93867
MCUR1 mitochondrial calcium uniporter regulator 1 2.85764
GPATCH8 G patch domain containing 8 2.77111
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.42562
ATMIN ATM interactor 2.35403
CSTA cystatin A (stefin A) 2.09501
DPH2 DPH2 homolog (S. cerevisiae) 2.06484
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.05522
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.01726

decreased expression

Symbol Name Standardized Value
NPDC1 neural proliferation, differentiation and control, 1 -5.09133
PMM2 phosphomannomutase 2 -4.2075
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -3.49634
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -3.25613
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.40621
BLNK B-cell linker -2.11054
TRPS1 trichorhinophalangeal syndrome I -2.10546
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -2.04501