CRCGN016_MCF10A.TP53.M_24H:N05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description glycidol 33.77 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

34 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:N05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STAP2 signal transducing adaptor family member 2 3.17413
PPARG peroxisome proliferator-activated receptor gamma 3.16446
C2CD2 C2 calcium-dependent domain containing 2 3.13645
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 3.09396
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 2.91797
HBA1 hemoglobin, alpha 1 2.86062
GATA3 GATA binding protein 3 2.78416
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.51169
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.28715
TBPL1 TBP-like 1 2.26687
FABP4 fatty acid binding protein 4, adipocyte 2.20446
MCUR1 mitochondrial calcium uniporter regulator 1 2.19309
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.11607
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 2.01682

decreased expression

Symbol Name Standardized Value
TUBA4A tubulin, alpha 4a -4.54548
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -4.53756
PCNA proliferating cell nuclear antigen -3.65271
PCCB propionyl CoA carboxylase, beta polypeptide -3.4095
PIH1D1 PIH1 domain containing 1 -3.32396
TM9SF3 transmembrane 9 superfamily member 3 -3.26363
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.01608
TRIB3 tribbles pseudokinase 3 -2.86343
TRAPPC3 trafficking protein particle complex 3 -2.79355
CD320 CD320 molecule -2.7235
HSPA8 heat shock 70kDa protein 8 -2.63646
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.37907
ZNF428 zinc finger protein 428 -2.19659
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 -2.19628
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 -2.16637
SNTA1 syntrophin, alpha 1 -2.12045
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -2.03767
BASP1 brain abundant, membrane attached signal protein 1 -2.02626
CLASRP CLK4-associating serine/arginine rich protein -2.02474
SPTBN4 spectrin, beta, non-erythrocytic 4 -2.01754