CRCGN016_MCF10A.TP53.M_24H:N10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description urethane 105.29 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:N10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MYLK myosin light chain kinase 4.96145
UBQLN2 ubiquilin 2 4.80647
ACAA1 acetyl-CoA acyltransferase 1 3.7174
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.77997
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 2.30638
CADM1 cell adhesion molecule 1 2.16125
SPARCL1 SPARC-like 1 (hevin) 2.08676

decreased expression

Symbol Name Standardized Value
ACOT9 acyl-CoA thioesterase 9 -4.59247
NLRP4 NLR family, pyrin domain containing 4 -3.72818
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.65344
ISOC1 isochorismatase domain containing 1 -2.64914
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.59237
STK25 serine/threonine kinase 25 -2.26457
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta -2.07295
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -2.03579