| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | urethane 11.7 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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57 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:N12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BZW2 | basic leucine zipper and W2 domains 2 | 4.09032 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.95124 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 3.61046 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 3.59935 |
| MYLK | myosin light chain kinase | 3.50861 |
| HBA1 | hemoglobin, alpha 1 | 3.47969 |
| KDM5D | lysine (K)-specific demethylase 5D | 3.45838 |
| MDN1 | MDN1, midasin homolog (yeast) | 3.00582 |
| TLCD3A | TLC domain containing 3A | 2.92661 |
| CHEK2 | checkpoint kinase 2 | 2.90573 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.77567 |
| AGR2 | anterior gradient 2 | 2.60085 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 2.5912 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 2.56953 |
| NVL | nuclear VCP-like | 2.5607 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 2.49695 |
| WDR37 | WD repeat domain 37 | 2.42095 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 2.36194 |
| ATAD2B | ATPase family, AAA domain containing 2B | 2.3268 |
| HBB | hemoglobin, beta | 2.2986 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | 2.23555 |
| GZMK | granzyme K (granzyme 3; tryptase II) | 2.1852 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 2.17969 |
| MCM10 | minichromosome maintenance complex component 10 | 2.15397 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 2.14493 |
| TSTD2 | thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 | 2.12574 |
| GPR65 | G protein-coupled receptor 65 | 2.05993 |
| MPC1 | mitochondrial pyruvate carrier 1 | 2.03938 |
| TGFBR3 | transforming growth factor, beta receptor III | 2.03768 |
| TSLIG3A | tRNA splicing ligase complex subunit 3A | 2.0106 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TRAPPC3 | trafficking protein particle complex 3 | -4.75434 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -4.42349 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -4.17996 |
| ANKRD10 | ankyrin repeat domain 10 | -4.04368 |
| MSMO1 | methylsterol monooxygenase 1 | -3.92541 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -3.82719 |
| MTERF3 | mitochondrial transcription termination factor 3 | -3.74983 |
| LYPLA1 | lysophospholipase I | -3.56939 |
| MEAF6 | MYST/Esa1-associated factor 6 | -3.3638 |
| KDM5C | lysine (K)-specific demethylase 5C | -3.08366 |
| LOC124905557 | eukaryotic translation initiation factor 1A, X-chromosomal | -2.92689 |
| PUDP | pseudouridine 5'-phosphatase | -2.55686 |
| SORBS3 | sorbin and SH3 domain containing 3 | -2.40592 |
| PAIP1 | poly(A) binding protein interacting protein 1 | -2.34043 |
| SQLE | squalene epoxidase | -2.31665 |
| MRPS15 | mitochondrial ribosomal protein S15 | -2.27543 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -2.20205 |
| TOM1L1 | target of myb1 (chicken)-like 1 | -2.19972 |
| EXT1 | exostosin glycosyltransferase 1 | -2.17392 |
| CLASRP | CLK4-associating serine/arginine rich protein | -2.17062 |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) | -2.12987 |
| MVD | mevalonate (diphospho) decarboxylase | -2.05842 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 | -2.05638 |
| HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 | -2.0507 |
| SMAD5 | SMAD family member 5 | -2.03679 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -2.01724 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | -2.01019 |
