CRCGN016_MCF10A.TP53.M_24H:N17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description vinylidene chloride 35.1 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

48 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:N17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FKBP14 FK506 binding protein 14, 22 kDa 7.87075
GPER1 G protein-coupled estrogen receptor 1 4.69245
KLHL9 kelch-like family member 9 4.49183
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 3.50553
SLC16A4 solute carrier family 16, member 4 3.21037
CCL2 chemokine (C-C motif) ligand 2 3.1988
SPAG4 sperm associated antigen 4 2.74644
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.6749
CETN3 centrin, EF-hand protein, 3 2.59648
SREK1IP1 SREK1-interacting protein 1 2.51333
CCP110 centriolar coiled coil protein 110kDa 2.50741
YIPF5 Yip1 domain family, member 5 2.41204
WIF1 WNT inhibitory factor 1 2.35667
CTSZ cathepsin Z 2.30577
GLIPR1 GLI pathogenesis-related 1 2.25632
RCN3 reticulocalbin 3, EF-hand calcium binding domain 2.23249
MEGF8 multiple EGF-like-domains 8 2.21428
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 2.19843
LGMN legumain 2.16898
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 2.14805
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 2.13808
APLP2 amyloid beta (A4) precursor-like protein 2 2.13645
PITPNB phosphatidylinositol transfer protein, beta 2.12338
TSPAN5 tetraspanin 5 2.10592
OXR1 oxidation resistance 1 2.10262
FAT4 FAT atypical cadherin 4 2.08561
HAS2 hyaluronan synthase 2 2.05929
SNX19 sorting nexin 19 2.05588
SLC31A1 solute carrier family 31 (copper transporter), member 1 2.02969
SYNJ2BP synaptojanin 2 binding protein 2.02607
CADM1 cell adhesion molecule 1 2.02298
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.0204
NAP1L3 nucleosome assembly protein 1-like 3 2.01723
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.01309

decreased expression

Symbol Name Standardized Value
CCDC86 coiled-coil domain containing 86 -5.14303
KIF14 kinesin family member 14 -4.60231
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.38379
PCNA proliferating cell nuclear antigen -2.83754
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.77141
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -2.28955
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.28003
E2F6 E2F transcription factor 6 -2.21433
KCNK1 potassium channel, two pore domain subfamily K, member 1 -2.19906
RRP1B ribosomal RNA processing 1B -2.158
IGFBP7 insulin-like growth factor binding protein 7 -2.09909
NT5DC2 5'-nucleotidase domain containing 2 -2.04722
SGK1 serum/glucocorticoid regulated kinase 1 -2.02893
CDC73 cell division cycle 73 -2.00535