CRCGN016_MCF10A.TP53.M_24H:N18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description vinylidene chloride 11.7 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

60 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:N18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SNAP25 synaptosomal-associated protein, 25kDa 4.16669
MAP7 microtubule-associated protein 7 4.13547
CCP110 centriolar coiled coil protein 110kDa 4.08471
AGR2 anterior gradient 2 3.97535
CXCL2 chemokine (C-X-C motif) ligand 2 3.87123
KLHL21 kelch-like family member 21 3.55327
KCTD5 potassium channel tetramerization domain containing 5 3.1791
STAMBP STAM binding protein 3.1321
CADM1 cell adhesion molecule 1 2.87073
PLS1 plastin 1 2.69187
RNF103-CHMP3 RNF103-CHMP3 readthrough 2.65757
CORO1A coronin, actin binding protein, 1A 2.50862
KDM5D lysine (K)-specific demethylase 5D 2.39946
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 2.28759
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 2.23829
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 2.23471
TRIP4 thyroid hormone receptor interactor 4 2.18988
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.15844
CRYZL1 crystallin, zeta (quinone reductase)-like 1 2.14521
GPN1 GPN-loop GTPase 1 2.05295
CGRRF1 cell growth regulator with ring finger domain 1 2.04815
PI15 peptidase inhibitor 15 2.04526
OXR1 oxidation resistance 1 2.03478
PAIP2B poly(A) binding protein interacting protein 2B 2.02285
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 2.01301

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -4.54949
MT1X metallothionein 1X -3.90798
HEATR1 HEAT repeat containing 1 -3.82073
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.69186
FPGS folylpolyglutamate synthase -3.60013
BAG3 BCL2-associated athanogene 3 -3.50428
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.35054
TM9SF3 transmembrane 9 superfamily member 3 -3.09163
LRRC41 leucine rich repeat containing 41 -2.80659
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.78605
DTX2 deltex 2, E3 ubiquitin ligase -2.74368
ATOX1 antioxidant 1 copper chaperone -2.73221
ETFB electron-transfer-flavoprotein, beta polypeptide -2.70913
MYBBP1A MYB binding protein (P160) 1a -2.41508
CD81 CD81 molecule -2.38474
UBA1 ubiquitin-like modifier activating enzyme 1 -2.2601
KRT14 keratin 14, type I -2.23996
CABIN1 calcineurin binding protein 1 -2.20115
ADGRE5 adhesion G protein-coupled receptor E5 -2.16477
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific -2.15947
COG4 component of oligomeric golgi complex 4 -2.14561
TWF2 twinfilin actin binding protein 2 -2.13311
MT2A metallothionein 2A -2.12374
DDIT4 DNA-damage-inducible transcript 4 -2.12282
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -2.11483
PFN1 profilin 1 -2.11272
DHRS7 dehydrogenase/reductase (SDR family) member 7 -2.10008
TIMP1 TIMP metallopeptidase inhibitor 1 -2.09626
MVD mevalonate (diphospho) decarboxylase -2.08941
TUBA4A tubulin, alpha 4a -2.07416
GALT galactose-1-phosphate uridylyltransferase -2.05823
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -2.05589
POLD4 polymerase (DNA-directed), delta 4, accessory subunit -2.0259
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 -2.01497
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -2.0062