| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | fenthion 105.64 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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132 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:N19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPER1 | G protein-coupled estrogen receptor 1 | 5.52226 |
| WFS1 | Wolfram syndrome 1 (wolframin) | 5.50435 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 5.43353 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 5.31263 |
| STK10 | serine/threonine kinase 10 | 4.85338 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 4.15852 |
| WIF1 | WNT inhibitory factor 1 | 4.11436 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 3.97858 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 3.58235 |
| CCDC85B | coiled-coil domain containing 85B | 3.55435 |
| CCNA1 | cyclin A1 | 3.20564 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 3.10292 |
| NUCB2 | nucleobindin 2 | 3.08155 |
| LOC122526780 | uncharacterized LOC122526780 | 2.78317 |
| PAGE4 | P antigen family, member 4 (prostate associated) | 2.76295 |
| PLSCR1 | phospholipid scramblase 1 | 2.68871 |
| CSH2 | chorionic somatomammotropin hormone 2 | 2.68487 |
| TSPYL5 | TSPY-like 5 | 2.65617 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | 2.55759 |
| FUBP3 | far upstream element (FUSE) binding protein 3 | 2.53472 |
| GAR1 | GAR1 ribonucleoprotein | 2.525 |
| WRN | Werner syndrome, RecQ helicase-like | 2.44515 |
| CFAP69 | cilia and flagella associated protein 69 | 2.44142 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | 2.41011 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 2.40619 |
| ACBD3 | acyl-CoA binding domain containing 3 | 2.34122 |
| DKK4 | dickkopf WNT signaling pathway inhibitor 4 | 2.33219 |
| PPWD1 | peptidylprolyl isomerase domain and WD repeat containing 1 | 2.3274 |
| NUP153 | nucleoporin 153kDa | 2.31188 |
| MEF2C | myocyte enhancer factor 2C | 2.31138 |
| CHN1 | chimerin 1 | 2.30184 |
| FMR1 | fragile X mental retardation 1 | 2.29635 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 2.29451 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 | 2.284 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 | 2.28177 |
| PTPRN | protein tyrosine phosphatase, receptor type, N | 2.27174 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase | 2.25483 |
| SLC6A12 | solute carrier family 6 (neurotransmitter transporter), member 12 | 2.22819 |
| RFPL2 | ret finger protein-like 2 | 2.20482 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 2.19409 |
| MXRA8 | matrix-remodelling associated 8 | 2.19157 |
| SATB1 | SATB homeobox 1 | 2.17503 |
| HBB | hemoglobin, beta | 2.1582 |
| SLC8A2 | solute carrier family 8 (sodium/calcium exchanger), member 2 | 2.14973 |
| KRT23 | keratin 23, type I | 2.14612 |
| CRABP1 | cellular retinoic acid binding protein 1 | 2.14 |
| MMP9 | matrix metallopeptidase 9 | 2.13514 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | 2.13426 |
| IRGQ | immunity-related GTPase family, Q | 2.13267 |
| NES | nestin | 2.13111 |
| TAF11 | TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa | 2.11261 |
| GUCY1B1 | guanylate cyclase 1 soluble subunit beta 1 | 2.10797 |
| ZNF85 | zinc finger protein 85 | 2.10447 |
| LNX1 | ligand of numb-protein X 1, E3 ubiquitin protein ligase | 2.09887 |
| SMAD1 | SMAD family member 1 | 2.09573 |
| CADM1 | cell adhesion molecule 1 | 2.08262 |
| NDST3 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 | 2.08075 |
| DEFA3 | defensin, alpha 3, neutrophil-specific | 2.07937 |
| EOLA1 | endothelium and lymphocyte associated ASCH domain 1 | 2.05818 |
| DHX16 | DEAH (Asp-Glu-Ala-His) box polypeptide 16 | 2.05424 |
| PRAMEF12 | PRAME family member 12 | 2.045 |
| EFHD1 | EF-hand domain family, member D1 | 2.03832 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | 2.03629 |
| FSHB | follicle stimulating hormone, beta polypeptide | 2.03247 |
| FKBPL | FK506 binding protein like | 2.02516 |
| COL11A1 | collagen, type XI, alpha 1 | 2.01841 |
| BEX4 | brain expressed, X-linked 4 | 2.01775 |
| MMP8 | matrix metallopeptidase 8 | 2.01552 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 | 2.0078 |
| RNF115 | ring finger protein 115 | 2.00455 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 2.00373 |
| HOXA10-HOXA9 | HOXA10-HOXA9 readthrough | 2.00329 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VAT1 | vesicle amine transport 1 | -6.0569 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -5.19211 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -5.01036 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -4.96983 |
| ANXA2 | annexin A2 | -4.91505 |
| ANKRD10 | ankyrin repeat domain 10 | -3.80852 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -3.78038 |
| TUBA4A | tubulin, alpha 4a | -3.2137 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | -3.14487 |
| HSPB1 | heat shock 27kDa protein 1 | -3.05994 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.05064 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -3.04792 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.9303 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -2.8613 |
| PLK1 | polo-like kinase 1 | -2.76208 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -2.63494 |
| SNRPN | small nuclear ribonucleoprotein polypeptide N | -2.61769 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -2.61296 |
| CYCS | cytochrome c, somatic | -2.53844 |
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 | -2.50229 |
| COTL1 | coactosin-like F-actin binding protein 1 | -2.48348 |
| ACOT9 | acyl-CoA thioesterase 9 | -2.46286 |
| GPR171 | G protein-coupled receptor 171 | -2.43771 |
| VPS4A | vacuolar protein sorting 4 homolog A (S. cerevisiae) | -2.43335 |
| HSD17B10 | hydroxysteroid (17-beta) dehydrogenase 10 | -2.42012 |
| ADI1 | acireductone dioxygenase 1 | -2.40943 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | -2.3962 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -2.3894 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.37996 |
| MRPS16 | mitochondrial ribosomal protein S16 | -2.37368 |
| CCDC51 | coiled-coil domain containing 51 | -2.37087 |
| NAXD | NAD(P)HX dehydratase | -2.33541 |
| CIAO2B | cytosolic iron-sulfur assembly component 2B | -2.29796 |
| MPST | mercaptopyruvate sulfurtransferase | -2.24231 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -2.22492 |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase | -2.22282 |
| HOXC6 | homeobox C6 | -2.2143 |
| PIR | pirin (iron-binding nuclear protein) | -2.19953 |
| UQCRC1 | ubiquinol-cytochrome c reductase core protein I | -2.19325 |
| MAPK3 | mitogen-activated protein kinase 3 | -2.17961 |
| CARS2 | cysteinyl-tRNA synthetase 2, mitochondrial (putative) | -2.17624 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -2.14888 |
| MVP | major vault protein | -2.11383 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -2.1099 |
| MUC13 | mucin 13, cell surface associated | -2.09401 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 | -2.09391 |
| PRKCD | protein kinase C, delta | -2.08028 |
| TWF2 | twinfilin actin binding protein 2 | -2.08025 |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | -2.0802 |
| RAB5IF | RAB5 interacting factor | -2.06673 |
| KRT14 | keratin 14, type I | -2.06638 |
| MISP | mitotic spindle positioning | -2.0593 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -2.05625 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | -2.04128 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit | -2.03642 |
| LAMTOR2 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 | -2.0342 |
| SH3D19 | SH3 domain containing 19 | -2.03351 |
| PROCR | protein C receptor, endothelial | -2.02626 |
| DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 | -2.02555 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 | -2.0005 |
