CRCGN016_MCF10A.TP53.M_24H:N20 Gene Set
Genes
27 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:N20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
5.55386
|
|
WFS1
|
Wolfram syndrome 1 (wolframin)
|
5.08052
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
4.98933
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
4.78152
|
|
IDE
|
insulin-degrading enzyme
|
4.29495
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
3.81997
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
3.3288
|
|
AGR2
|
anterior gradient 2
|
3.22081
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.94084
|
|
MMP1
|
matrix metallopeptidase 1
|
2.85721
|
|
WIF1
|
WNT inhibitory factor 1
|
2.34334
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.34173
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.27108
|
|
RBM34
|
RNA binding motif protein 34
|
2.22932
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.21521
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.04408
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
2.00546
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.12928
|
|
GRN
|
granulin
|
-2.89076
|
|
KRT14
|
keratin 14, type I
|
-2.8659
|
|
GMPR2
|
guanosine monophosphate reductase 2
|
-2.57958
|
|
THTPA
|
thiamine triphosphatase
|
-2.51853
|
|
SDHA
|
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
|
-2.27617
|
|
TINF2
|
TERF1 (TRF1)-interacting nuclear factor 2
|
-2.15593
|
|
METTL17
|
methyltransferase like 17
|
-2.14112
|
|
CSK
|
c-src tyrosine kinase
|
-2.03848
|
|
TUBA4A
|
tubulin, alpha 4a
|
-2.02053
|
