CRCGN016_MCF10A.TP53.M_24H:N21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description fenthion 11.74 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:N21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
BAMBI BMP and activin membrane-bound inhibitor 5.85786
SSBP2 single-stranded DNA binding protein 2 4.98321
ZNF318 zinc finger protein 318 4.29309
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 3.2933
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 3.06694
HBA1 hemoglobin, alpha 1 3.01068
LGMN legumain 2.34045
TRAF1 TNF receptor-associated factor 1 2.31817
CHSY1 chondroitin sulfate synthase 1 2.16409
ISOC1 isochorismatase domain containing 1 2.14707

decreased expression

Symbol Name Standardized Value
CD44 CD44 molecule (Indian blood group) -4.33377
STXBP2 syntaxin binding protein 2 -3.86354
HSPA8 heat shock 70kDa protein 8 -3.39495
CAPN2 calpain 2, (m/II) large subunit -3.29851
REEP5 receptor accessory protein 5 -3.24912
NVL nuclear VCP-like -2.82959
KRT14 keratin 14, type I -2.79631
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.74448
TIMP1 TIMP metallopeptidase inhibitor 1 -2.67798
TUBA4A tubulin, alpha 4a -2.65125
ANXA2 annexin A2 -2.5121
GRN granulin -2.28639
ADAM15 ADAM metallopeptidase domain 15 -2.21576
NECAB3 N-terminal EF-hand calcium binding protein 3 -2.20041
HSPB1 heat shock 27kDa protein 1 -2.19353
ULBP2 UL16 binding protein 2 -2.18629
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.04798
SIRT7 sirtuin 7 -2.02487
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.01125