| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | UnTrt perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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183 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:O01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IDE | insulin-degrading enzyme | 6.07412 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.39182 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 4.93479 |
| CNPY3 | canopy FGF signaling regulator 3 | 4.65866 |
| WIF1 | WNT inhibitory factor 1 | 4.30083 |
| DDN | dendrin | 3.39195 |
| BZW2 | basic leucine zipper and W2 domains 2 | 3.3317 |
| CLEC7A | C-type lectin domain family 7, member A | 2.90696 |
| COMP | cartilage oligomeric matrix protein | 2.87096 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 2.84631 |
| C5 | complement component 5 | 2.82858 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | 2.80541 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 2.74923 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 2.71455 |
| COL11A1 | collagen, type XI, alpha 1 | 2.6777 |
| GHR | growth hormone receptor | 2.67734 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 2.63752 |
| HPCA | hippocalcin | 2.61757 |
| GLRX2 | glutaredoxin 2 | 2.5159 |
| SMNDC1 | survival motor neuron domain containing 1 | 2.50558 |
| KPLCE | KPRP N-terminal and LCE C-terminal like protein | 2.45078 |
| CNPY3-GNMT | CNPY3-GNMT readthrough | 2.42375 |
| HDAC2 | histone deacetylase 2 | 2.42009 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 2.39961 |
| EREG | epiregulin | 2.39388 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 2.38194 |
| ISOC1 | isochorismatase domain containing 1 | 2.36918 |
| CCP110 | centriolar coiled coil protein 110kDa | 2.34548 |
| RIPPLY2-CYB5R4 | RIPPLY2-CYB5R4 readthrough | 2.34534 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 2.31645 |
| LGMN | legumain | 2.29961 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 2.29662 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | 2.26742 |
| TEX11 | testis expressed 11 | 2.26694 |
| TERT | telomerase reverse transcriptase | 2.26416 |
| TXNDC9 | thioredoxin domain containing 9 | 2.25558 |
| TMED7 | transmembrane emp24 protein transport domain containing 7 | 2.25371 |
| LCE2B | late cornified envelope 2B | 2.24814 |
| H2BC12 | H2B clustered histone 12 | 2.24399 |
| SMIM41 | small integral membrane protein 41 | 2.23932 |
| RSPH6A | radial spoke head 6 homolog A (Chlamydomonas) | 2.23891 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 2.23328 |
| GPR88 | G protein-coupled receptor 88 | 2.22884 |
| RGS14 | regulator of G-protein signaling 14 | 2.21463 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 2.21424 |
| CD48 | CD48 molecule | 2.21021 |
| FGFR4 | fibroblast growth factor receptor 4 | 2.19796 |
| TFDP3 | transcription factor Dp family, member 3 | 2.19461 |
| MINPP1 | multiple inositol-polyphosphate phosphatase 1 | 2.19304 |
| CRLF3 | cytokine receptor-like factor 3 | 2.18833 |
| RAB21 | RAB21, member RAS oncogene family | 2.18307 |
| DCK | deoxycytidine kinase | 2.18054 |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 | 2.17418 |
| PLK2 | polo-like kinase 2 | 2.1727 |
| PLSCR1 | phospholipid scramblase 1 | 2.17206 |
| TGFB3 | transforming growth factor, beta 3 | 2.16915 |
| CD36 | CD36 molecule (thrombospondin receptor) | 2.16614 |
| CETN3 | centrin, EF-hand protein, 3 | 2.15903 |
| RAP2C | RAP2C, member of RAS oncogene family | 2.15855 |
| MYZAP | myocardial zonula adherens protein | 2.15854 |
| EVI2A | ecotropic viral integration site 2A | 2.15009 |
| ZNF652 | zinc finger protein 652 | 2.14766 |
| EEF1E1 | eukaryotic translation elongation factor 1 epsilon 1 | 2.14103 |
| PAK1IP1 | PAK1 interacting protein 1 | 2.13445 |
| NCDN | neurochondrin | 2.11752 |
| CADM1 | cell adhesion molecule 1 | 2.11171 |
| TOR4A | torsin family 4, member A | 2.10455 |
| TXNL4B | thioredoxin-like 4B | 2.10302 |
| MSMB | microseminoprotein, beta- | 2.10227 |
| RIDA | reactive intermediate imine deaminase A homolog | 2.09198 |
| LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 | 2.09044 |
| DPH2 | DPH2 homolog (S. cerevisiae) | 2.07214 |
| SBDS | Shwachman-Bodian-Diamond syndrome | 2.06904 |
| H2BC4 | H2B clustered histone 4 | 2.06695 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 | 2.06328 |
| IGSF6 | immunoglobulin superfamily, member 6 | 2.06062 |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 | 2.05871 |
| TEX30 | testis expressed 30 | 2.05604 |
| FGL1 | fibrinogen-like 1 | 2.0552 |
| CERT1 | ceramide transporter 1 | 2.0535 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 2.05171 |
| TLK2 | tousled-like kinase 2 | 2.04641 |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) | 2.04259 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) | 2.04158 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 2.04091 |
| LOC128966586 | pepsin A-4-like | 2.03779 |
| PSMA2 | proteasome (prosome, macropain) subunit, alpha type, 2 | 2.03522 |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) | 2.03514 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 2.03124 |
| PDE1B | phosphodiesterase 1B, calmodulin-dependent | 2.02571 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 2.02066 |
| TMEM70 | transmembrane protein 70 | 2.01811 |
| H2BC9 | H2B clustered histone 9 | 2.01782 |
| PDCD10 | programmed cell death 10 | 2.00975 |
| NANOS3 | nanos homolog 3 (Drosophila) | 2.00005 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -4.33875 |
| TUBA4A | tubulin, alpha 4a | -4.19251 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -4.12586 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -3.8945 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -3.85839 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.69157 |
| MT1X | metallothionein 1X | -3.67138 |
| KRT14 | keratin 14, type I | -3.6648 |
| DDIT4 | DNA-damage-inducible transcript 4 | -3.50571 |
| MSN | moesin | -3.49247 |
| HSD17B10 | hydroxysteroid (17-beta) dehydrogenase 10 | -3.44228 |
| PIH1D1 | PIH1 domain containing 1 | -3.43457 |
| MT2A | metallothionein 2A | -3.40106 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | -3.39443 |
| TUBB6 | tubulin, beta 6 class V | -3.17051 |
| LRP10 | low density lipoprotein receptor-related protein 10 | -3.13571 |
| ARFIP2 | ADP-ribosylation factor interacting protein 2 | -3.11188 |
| HSPB1 | heat shock 27kDa protein 1 | -3.03475 |
| ATG9A | autophagy related 9A | -3.03235 |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | -3.02106 |
| ATP6AP1 | ATPase, H+ transporting, lysosomal accessory protein 1 | -3.01725 |
| FAM50A | family with sequence similarity 50, member A | -2.91261 |
| TKT | transketolase | -2.89051 |
| CD81 | CD81 molecule | -2.87096 |
| HMG20B | high mobility group 20B | -2.85586 |
| RNF167 | ring finger protein 167 | -2.85268 |
| TSPAN4 | tetraspanin 4 | -2.82993 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -2.81668 |
| ANXA2 | annexin A2 | -2.81396 |
| VAT1 | vesicle amine transport 1 | -2.78572 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -2.74547 |
| NDRG1 | N-myc downstream regulated 1 | -2.71151 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | -2.70758 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit | -2.67906 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.61311 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -2.61068 |
| PLK1 | polo-like kinase 1 | -2.57334 |
| F8A2 | coagulation factor VIII-associated 2 | -2.50385 |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase | -2.49598 |
| ECH1 | enoyl CoA hydratase 1, peroxisomal | -2.48518 |
| MVP | major vault protein | -2.46446 |
| TWF2 | twinfilin actin binding protein 2 | -2.45856 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.44735 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) | -2.43105 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -2.42675 |
| HDLBP | high density lipoprotein binding protein | -2.40805 |
| RBM6 | RNA binding motif protein 6 | -2.40608 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -2.37619 |
| COQ9 | coenzyme Q9 | -2.3529 |
| ETHE1 | ethylmalonic encephalopathy 1 | -2.35248 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -2.35053 |
| PNKP | polynucleotide kinase 3'-phosphatase | -2.34025 |
| TUFM | Tu translation elongation factor, mitochondrial | -2.32824 |
| FAH | fumarylacetoacetate hydrolase (fumarylacetoacetase) | -2.32526 |
| PTOV1 | prostate tumor overexpressed 1 | -2.29404 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | -2.28608 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -2.27053 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -2.24611 |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | -2.24495 |
| ILK | integrin-linked kinase | -2.23382 |
| CDC25B | cell division cycle 25B | -2.21732 |
| NDUFS2 | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) | -2.20921 |
| CAPN2 | calpain 2, (m/II) large subunit | -2.20897 |
| COG4 | component of oligomeric golgi complex 4 | -2.20257 |
| GABARAP | GABA(A) receptor-associated protein | -2.18756 |
| VPS4A | vacuolar protein sorting 4 homolog A (S. cerevisiae) | -2.18481 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -2.17545 |
| GRN | granulin | -2.17074 |
| FAM3A | family with sequence similarity 3, member A | -2.16196 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -2.15711 |
| CHMP4B | charged multivesicular body protein 4B | -2.15151 |
| AXIN1 | axin 1 | -2.14617 |
| SUN2 | Sad1 and UNC84 domain containing 2 | -2.13866 |
| UQCRC1 | ubiquinol-cytochrome c reductase core protein I | -2.11032 |
| ATP5F1B | ATP synthase F1 subunit beta | -2.10236 |
| NDUFS8 | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) | -2.10115 |
| TBC1D10B | TBC1 domain family, member 10B | -2.09742 |
| KLC1 | kinesin light chain 1 | -2.08738 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | -2.08306 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | -2.0741 |
| CD151 | CD151 molecule (Raph blood group) | -2.07284 |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 | -2.07198 |
| HOXA5 | homeobox A5 | -2.04489 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | -2.04398 |
| RABAC1 | Rab acceptor 1 (prenylated) | -2.04121 |
| PRAF2 | PRA1 domain family, member 2 | -2.02853 |
| FLNA | filamin A, alpha | -2.01528 |
| TNIP1 | TNFAIP3 interacting protein 1 | -2.01187 |
