| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | UnTrt perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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69 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:O05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 5.07955 |
| CCDC92 | coiled-coil domain containing 92 | 4.9128 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 4.86225 |
| E2F2 | E2F transcription factor 2 | 4.1872 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 3.6005 |
| GRB10 | growth factor receptor-bound protein 10 | 3.35458 |
| SNX11 | sorting nexin 11 | 3.27845 |
| GPATCH8 | G patch domain containing 8 | 2.88665 |
| HS6ST1 | heparan sulfate 6-O-sulfotransferase 1 | 2.3626 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 2.34978 |
| AQP5 | aquaporin 5 | 2.26695 |
| NPPB | natriuretic peptide B | 2.2074 |
| ANXA3 | annexin A3 | 2.20595 |
| CENPC | centromere protein C | 2.1941 |
| ATMIN | ATM interactor | 2.18353 |
| SOX1 | SRY (sex determining region Y)-box 1 | 2.1812 |
| CPAP | centrosome assembly and centriole elongation protein | 2.17305 |
| MTA1 | metastasis associated 1 | 2.14297 |
| NKX2-2 | NK2 homeobox 2 | 2.13765 |
| CBX1 | chromobox homolog 1 | 2.11965 |
| NTAQ1 | N-terminal glutamine amidase 1 | 2.11865 |
| HSD17B3 | hydroxysteroid (17-beta) dehydrogenase 3 | 2.1179 |
| PANX1 | pannexin 1 | 2.09875 |
| KCTD11 | potassium channel tetramerization domain containing 11 | 2.0961 |
| PMP2 | peripheral myelin protein 2 | 2.0935 |
| PAQR6 | progestin and adipoQ receptor family member VI | 2.07385 |
| MEX3D | mex-3 RNA binding family member D | 2.06435 |
| BTBD1 | BTB (POZ) domain containing 1 | 2.0482 |
| CLPTM1 | cleft lip and palate associated transmembrane protein 1 | 2.04445 |
| RFX4 | regulatory factor X, 4 (influences HLA class II expression) | 2.03795 |
| PRND | prion protein 2 (dublet) | 2.02845 |
| CXCR5 | chemokine (C-X-C motif) receptor 5 | 2.02533 |
| SNTG2 | syntrophin, gamma 2 | 2.02445 |
| DTYMK | deoxythymidylate kinase (thymidylate kinase) | 2.02425 |
| SELENOF | selenoprotein F | 2.02035 |
| ITGAV | integrin, alpha V | 2.01895 |
| FASTKD3 | FAST kinase domains 3 | 2.01355 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 2.00415 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 2.002 |
| Symbol | Name | Standardized Value |
|---|---|---|
| C2CD5 | C2 calcium-dependent domain containing 5 | -5.35575 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | -4.7872 |
| DNM1L | dynamin 1-like | -4.75905 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -4.72135 |
| CANT1 | calcium activated nucleotidase 1 | -4.68157 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial | -4.48225 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -3.86685 |
| NOSIP | nitric oxide synthase interacting protein | -3.7728 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -3.67445 |
| SORBS3 | sorbin and SH3 domain containing 3 | -3.09653 |
| STK38L | serine/threonine kinase 38 like | -2.69425 |
| INTS13 | integrator complex subunit 13 | -2.6849 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | -2.56535 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -2.3314 |
| CISH | cytokine inducible SH2-containing protein | -2.29925 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | -2.2737 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -2.22575 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase | -2.224 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -2.18605 |
| ATP11B | ATPase, class VI, type 11B | -2.17685 |
| KRT14 | keratin 14, type I | -2.16745 |
| SFMBT1 | Scm-like with four mbt domains 1 | -2.1032 |
| PPT2 | palmitoyl-protein thioesterase 2 | -2.0994 |
| ATP6V1F | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F | -2.0779 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 | -2.05925 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B | -2.05285 |
| TRMT1L | tRNA methyltransferase 1 homolog (S. cerevisiae)-like | -2.05005 |
| TUSC3 | tumor suppressor candidate 3 | -2.02395 |
| IL10RB | interleukin 10 receptor, beta | -2.00325 |
| COQ9 | coenzyme Q9 | -2.00205 |
