CRCGN016_MCF10A.TP53.M_24H:O06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description UnTrt perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:O06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AXIN1 axin 1 5.196
ABHD6 abhydrolase domain containing 6 4.99142
CARMIL1 capping protein regulator and myosin 1 linker 1 4.77705
ADO 2-aminoethanethiol (cysteamine) dioxygenase 4.75278
CCL2 chemokine (C-C motif) ligand 2 4.7477
LYN LYN proto-oncogene, Src family tyrosine kinase 4.16678
HBA1 hemoglobin, alpha 1 3.20225
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.9801
TBPL1 TBP-like 1 2.82625
NRBF2 nuclear receptor binding factor 2 2.46925
NEUROD6 neuronal differentiation 6 2.4294
ACAA1 acetyl-CoA acyltransferase 1 2.17083
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa 2.13645
STAB2 stabilin 2 2.0883
CCNE2 cyclin E2 2.03445
PAX6 paired box 6 2.00815

decreased expression

Symbol Name Standardized Value
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -5.7361
DHRS7 dehydrogenase/reductase (SDR family) member 7 -5.69255
UBE3C ubiquitin protein ligase E3C -4.6847
KDM3A lysine (K)-specific demethylase 3A -2.5977
TOR1A torsin family 1, member A (torsin A) -2.47032
HLA-F major histocompatibility complex, class I, F -2.42193
BASP1 brain abundant, membrane attached signal protein 1 -2.3019
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.28255
HLA-G major histocompatibility complex, class I, G -2.24234
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -2.2057