CRCGN016_MCF10A.TP53.M_24H:O09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description BRD-K61463582 10.94 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

508 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:O09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 8.76231
PPP1R13B protein phosphatase 1, regulatory subunit 13B 5.17954
COMP cartilage oligomeric matrix protein 5.0366
E2F2 E2F transcription factor 2 4.8687
KCTD5 potassium channel tetramerization domain containing 5 4.53027
COL11A1 collagen, type XI, alpha 1 4.41372
GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 3.55082
CDC73 cell division cycle 73 3.46251
CADM1 cell adhesion molecule 1 3.45246
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 3.3236
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 3.23069
RSAD2 radical S-adenosyl methionine domain containing 2 3.05038
MORC3 MORC family CW-type zinc finger 3 3.0063
NKX2-1 NK2 homeobox 1 2.94207
EPHX3 epoxide hydrolase 3 2.94184
DGKB diacylglycerol kinase, beta 90kDa 2.93411
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 2.91714
LYRM1 LYR motif containing 1 2.90301
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 2.88141
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 2.88117
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 2.86174
TMEM165 transmembrane protein 165 2.84894
DOCK3 dedicator of cytokinesis 3 2.84886
HAUS3 HAUS augmin-like complex, subunit 3 2.84832
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 2.84758
RYR2 ryanodine receptor 2 (cardiac) 2.84534
BCOR BCL6 corepressor 2.79148
TG thyroglobulin 2.79084
NELL1 NEL-like 1 (chicken) 2.78429
GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 2.76229
GET1 guided entry of tail-anchored proteins factor 1 2.75522
ARPP21 cAMP-regulated phosphoprotein, 21kDa 2.72698
TMBIM4 transmembrane BAX inhibitor motif containing 4 2.72164
RAB27B RAB27B, member RAS oncogene family 2.70857
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.70802
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 2.70165
C1GALT1C1 C1GALT1-specific chaperone 1 2.69816
MAP9 microtubule-associated protein 9 2.67283
PARM1 prostate androgen-regulated mucin-like protein 1 2.67218
UFM1 ubiquitin-fold modifier 1 2.65737
ENOPH1 enolase-phosphatase 1 2.65533
REV1 REV1, polymerase (DNA directed) 2.65468
GPR6 G protein-coupled receptor 6 2.64543
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 2.63209
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 2.63026
LIFR leukemia inhibitory factor receptor alpha 2.62139
RNF111 ring finger protein 111 2.61441
TMEM106B transmembrane protein 106B 2.60953
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 2.59805
ACP3 acid phosphatase 3 2.59166
INTS7 integrator complex subunit 7 2.59054
SATB1 SATB homeobox 1 2.58401
ADGRF5 adhesion G protein-coupled receptor F5 2.57895
FBXO34 F-box protein 34 2.57795
SGMS1 sphingomyelin synthase 1 2.57737
PLA2G12A phospholipase A2, group XIIA 2.57344
SMNDC1 survival motor neuron domain containing 1 2.57207
ITGA8 integrin, alpha 8 2.56526
FUBP3 far upstream element (FUSE) binding protein 3 2.56323
LTN1 listerin E3 ubiquitin protein ligase 1 2.56062
N4BP2L1 NEDD4 binding protein 2-like 1 2.55354
TRAPPC13 trafficking protein particle complex 13 2.55225
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 2.54698
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.54564
ZCCHC10 zinc finger, CCHC domain containing 10 2.54221
OBP2B odorant binding protein 2B 2.54132
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 2.5266
TCP10L t-complex 10-like 2.52618
TMA16 translation machinery associated 16 homolog (S. cerevisiae) 2.51818
PLPPR1 phospholipid phosphatase related 1 2.5117
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 2.50648
HEXB hexosaminidase B (beta polypeptide) 2.50202
ACP5 acid phosphatase 5, tartrate resistant 2.49767
ZNF280B zinc finger protein 280B 2.49635
ACTL6A actin-like 6A 2.49212
HAT1 histone acetyltransferase 1 2.48356
ANAPC10 anaphase promoting complex subunit 10 2.47839
HSFX2 heat shock transcription factor family, X linked 2 2.47809
BET1 Bet1 golgi vesicular membrane trafficking protein 2.47651
DUOX1 dual oxidase 1 2.46611
BICRAL BICRA like chromatin remodeling complex associated protein 2.45905
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 2.45426
PLXDC2 plexin domain containing 2 2.45351
PDYN prodynorphin 2.44991
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 2.44928
ZNF675 zinc finger protein 675 2.44799
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like 2.44637
DNAL4 dynein, axonemal, light chain 4 2.44597
RGS9BP regulator of G protein signaling 9 binding protein 2.44386
MEAF6 MYST/Esa1-associated factor 6 2.43836
MX1 MX dynamin-like GTPase 1 2.43338
LIMS1 LIM and senescent cell antigen-like domains 1 2.43311
CHMP5 charged multivesicular body protein 5 2.43274
KLK2 kallikrein-related peptidase 2 2.43145
SLC30A4 solute carrier family 30 (zinc transporter), member 4 2.42465
LRRC17 leucine rich repeat containing 17 2.42379
METTL4 methyltransferase like 4 2.42195
MGAT4C MGAT4 family, member C 2.42068
SPATA1 spermatogenesis associated 1 2.41871
IGSF6 immunoglobulin superfamily, member 6 2.41261
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.41245
BRDT bromodomain, testis-specific 2.41218
EPHA4 EPH receptor A4 2.40651
COL10A1 collagen, type X, alpha 1 2.40119
ALOX15B arachidonate 15-lipoxygenase, type B 2.39836
THNSL1 threonine synthase-like 1 (S. cerevisiae) 2.39311
OBP2A odorant binding protein 2A 2.39273
PDGFRL platelet-derived growth factor receptor-like 2.39212
LY6G6C lymphocyte antigen 6 complex, locus G6C 2.37967
CFAP69 cilia and flagella associated protein 69 2.37769
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa 2.37744
MOSPD1 motile sperm domain containing 1 2.3774
TSHR thyroid stimulating hormone receptor 2.37695
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 2.37588
NUP42 nucleoporin 42 2.37524
TXNDC15 thioredoxin domain containing 15 2.36497
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) 2.36226
PDCL3 phosducin-like 3 2.36077
S100A5 S100 calcium binding protein A5 2.36035
PLS1 plastin 1 2.35543
STEEP1 STING1 ER exit protein 1 2.35161
XAF1 XIAP associated factor 1 2.34973
EYA1 EYA transcriptional coactivator and phosphatase 1 2.34883
CCL2 chemokine (C-C motif) ligand 2 2.3478
MMP1 matrix metallopeptidase 1 2.34624
DRD1 dopamine receptor D1 2.3449
RNF139 ring finger protein 139 2.3428
GSG1 germ cell associated 1 2.34072
CTSO cathepsin O 2.33336
RNF19B ring finger protein 19B 2.32884
ALOX5 arachidonate 5-lipoxygenase 2.32696
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) 2.32403
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) 2.32246
CRYZ crystallin, zeta (quinone reductase) 2.3194
HOPX HOP homeobox 2.31549
RIT2 Ras-like without CAAX 2 2.3134
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 2.30993
AP1AR adaptor-related protein complex 1 associated regulatory protein 2.30772
SMC5 structural maintenance of chromosomes 5 2.3018
SP2 Sp2 transcription factor 2.3012
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 2.29853
EIF4E eukaryotic translation initiation factor 4E 2.29808
ZNF148 zinc finger protein 148 2.29437
LDOC1 leucine zipper, down-regulated in cancer 1 2.29345
TMEM184C transmembrane protein 184C 2.29344
TMEM50A transmembrane protein 50A 2.29181
UBXN8 UBX domain protein 8 2.29125
RHOT1 ras homolog family member T1 2.28855
COA3 cytochrome c oxidase assembly factor 3 2.2877
DIO2 deiodinase, iodothyronine, type II 2.28711
GPALPP1 GPALPP motifs containing 1 2.2855
MBIP MAP3K12 binding inhibitory protein 1 2.28317
PAK1IP1 PAK1 interacting protein 1 2.27827
MARK3 MAP/microtubule affinity-regulating kinase 3 2.27544
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 2.27205
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 2.26695
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 2.26285
ZSCAN16 zinc finger and SCAN domain containing 16 2.26276
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 2.26115
PAPOLG poly(A) polymerase gamma 2.25684
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.25617
SECISBP2 SECIS binding protein 2 2.25548
PRMT8 protein arginine methyltransferase 8 2.25365
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 2.24737
FAM153A family with sequence similarity 153, member A 2.24633
CPM carboxypeptidase M 2.24239
KISS1 KiSS-1 metastasis-suppressor 2.23848
FCHO1 FCH domain only 1 2.2379
PLCH1 phospholipase C, eta 1 2.23601
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 2.23436
NPTN neuroplastin 2.23416
DCC DCC netrin 1 receptor 2.22958
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 2.22922
TSSK2 testis-specific serine kinase 2 2.22728
TXNDC9 thioredoxin domain containing 9 2.22417
PACC1 proton activated chloride channel 1 2.22335
TIPRL TOR signaling pathway regulator 2.21938
HNRNPCL1 heterogeneous nuclear ribonucleoprotein C-like 1 2.21861
CDKL3 cyclin-dependent kinase-like 3 2.21857
ZMYM1 zinc finger, MYM-type 1 2.21422
RFPL2 ret finger protein-like 2 2.21394
SLC38A6 solute carrier family 38, member 6 2.21181
MEOX1 mesenchyme homeobox 1 2.20686
STAT4 signal transducer and activator of transcription 4 2.20657
JAM3 junctional adhesion molecule 3 2.20589
ZNF75D zinc finger protein 75D 2.20514
ZNF257 zinc finger protein 257 2.20157
WWC3 WWC family member 3 2.20115
SFTPB surfactant protein B 2.20094
FLCN folliculin 2.20081
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.19937
PTGDR prostaglandin D2 receptor (DP) 2.19798
ITGAV integrin, alpha V 2.19426
VSTM4 V-set and transmembrane domain containing 4 2.19008
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.1867
ARL15 ADP-ribosylation factor-like 15 2.18454
MNAT1 MNAT CDK-activating kinase assembly factor 1 2.18444
ZNF514 zinc finger protein 514 2.18085
CDKN2AIP CDKN2A interacting protein 2.17592
IFI6 interferon, alpha-inducible protein 6 2.17566
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) 2.17453
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 2.17401
KAT2B K(lysine) acetyltransferase 2B 2.17218
CNKSR2 connector enhancer of kinase suppressor of Ras 2 2.17194
RNF13 ring finger protein 13 2.16736
SEMG2 semenogelin II 2.16588
ACSL6 acyl-CoA synthetase long-chain family member 6 2.16191
NDN necdin, melanoma antigen (MAGE) family member 2.1613
PDE1A phosphodiesterase 1A, calmodulin-dependent 2.15869
PTPRD protein tyrosine phosphatase, receptor type, D 2.15851
NECAB2 N-terminal EF-hand calcium binding protein 2 2.15582
GRM2 glutamate receptor, metabotropic 2 2.15475
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 2.15155
WNT3 wingless-type MMTV integration site family, member 3 2.15049
TOX3 TOX high mobility group box family member 3 2.15014
PRR14L proline rich 14-like 2.14828
AP3M2 adaptor-related protein complex 3, mu 2 subunit 2.14818
ELOVL6 ELOVL fatty acid elongase 6 2.14791
MYO3A myosin IIIA 2.14476
ODAD2 outer dynein arm docking complex subunit 2 2.14361
IL3 interleukin 3 2.14272
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 2.1412
FBXO3 F-box protein 3 2.14098
ANXA7 annexin A7 2.13998
TMEM254 transmembrane protein 254 2.13732
UPP1 uridine phosphorylase 1 2.1369
UBE2D1 ubiquitin-conjugating enzyme E2D 1 2.13536
ZNF613 zinc finger protein 613 2.13001
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 2.12832
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 2.12747
PDZRN4 PDZ domain containing ring finger 4 2.12663
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 2.12516
HOXB8 homeobox B8 2.12461
MARCHF1 membrane associated ring-CH-type finger 1 2.12435
TUT7 terminal uridylyl transferase 7 2.12326
PLSCR2 phospholipid scramblase 2 2.12244
TULP2 tubby like protein 2 2.12215
ANKRD7 ankyrin repeat domain 7 2.11885
SYNGR4 synaptogyrin 4 2.11855
DCAF4 DDB1 and CUL4 associated factor 4 2.11826
BTC betacellulin 2.11636
OLAH oleoyl-ACP hydrolase 2.11251
PPA2 pyrophosphatase (inorganic) 2 2.11247
ZNF623 zinc finger protein 623 2.11186
TDRD12 tudor domain containing 12 2.1117
AIRIM AFG2 interacting ribosome maturation factor 2.10927
NACA2 nascent polypeptide-associated complex alpha subunit 2 2.1059
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 2.10341
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 2.10325
ZNF506 zinc finger protein 506 2.10207
H2BC14 H2B clustered histone 14 2.09802
NID2 nidogen 2 (osteonidogen) 2.09786
PDE10A phosphodiesterase 10A 2.09643
CXXC4 CXXC finger protein 4 2.09605
C2CD2 C2 calcium-dependent domain containing 2 2.09342
APIP APAF1 interacting protein 2.09261
SYN3 synapsin III 2.09197
MROH7 maestro heat-like repeat family member 7 2.09165
PCDH11X protocadherin 11 X-linked 2.09136
SFRP4 secreted frizzled-related protein 4 2.09127
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 2.09116
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 2.0908
KANSL1L KAT8 regulatory NSL complex subunit 1-like 2.09
DCSTAMP dendrocyte expressed seven transmembrane protein 2.08855
PITPNM3 PITPNM family member 3 2.0863
DEGS1 delta(4)-desaturase, sphingolipid 1 2.08565
TBC1D15 TBC1 domain family, member 15 2.08496
GPR21 G protein-coupled receptor 21 2.08333
YPEL1 yippee-like 1 (Drosophila) 2.08311
SLCO3A1 solute carrier organic anion transporter family, member 3A1 2.08184
AKT3 v-akt murine thymoma viral oncogene homolog 3 2.08163
LIN7B lin-7 homolog B (C. elegans) 2.08136
OMD osteomodulin 2.08014
CAMTA1 calmodulin binding transcription activator 1 2.07843
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 2.07696
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 2.07615
CDH8 cadherin 8, type 2 2.075
RIN2 Ras and Rab interactor 2 2.07475
CHIT1 chitinase 1 (chitotriosidase) 2.07465
DRC11 dynein regulatory complex subunit 11 2.06978
ZNF85 zinc finger protein 85 2.06786
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 2.06613
IFI44 interferon-induced protein 44 2.06596
TBL1Y transducin (beta)-like 1, Y-linked 2.06473
H2AP H2A.P histone 2.05822
SYNE1 spectrin repeat containing, nuclear envelope 1 2.05807
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B 2.05746
PAQR3 progestin and adipoQ receptor family member III 2.05611
NME5 NME/NM23 family member 5 2.05535
IMPG1 interphotoreceptor matrix proteoglycan 1 2.05532
PRKCI protein kinase C, iota 2.05491
IL4 interleukin 4 2.0545
USP27X ubiquitin specific peptidase 27, X-linked 2.05382
ZFPM2 zinc finger protein, FOG family member 2 2.05306
TAS2R4 taste receptor, type 2, member 4 2.05296
ANO3 anoctamin 3 2.05054
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 2.04993
RCVRN recoverin 2.04925
MAG myelin associated glycoprotein 2.04859
GLOD4 glyoxalase domain containing 4 2.0474
GJA5 gap junction protein, alpha 5, 40kDa 2.04582
TEX13A testis expressed 13A 2.04579
STEAP4 STEAP family member 4 2.04543
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 2.04373
GSAP gamma-secretase activating protein 2.04226
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 2.0398
PCSK2 proprotein convertase subtilisin/kexin type 2 2.03951
UNC50 unc-50 homolog (C. elegans) 2.0391
ZCCHC2 zinc finger, CCHC domain containing 2 2.03779
MAT2B methionine adenosyltransferase II, beta 2.03195
IFI44L interferon-induced protein 44-like 2.03162
PHOSPHO2-KLHL23 PHOSPHO2-KLHL23 readthrough 2.02732
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.02594
RNF170 ring finger protein 170 2.02481
BMP2K BMP2 inducible kinase 2.02082
ENC1 ectodermal-neural cortex 1 (with BTB domain) 2.01906
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 2.01473
PAGE4 P antigen family, member 4 (prostate associated) 2.01429
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 2.01424
RAP2C RAP2C, member of RAS oncogene family 2.01242
JCHAIN joining chain of multimeric IgA and IgM 2.01234
PENK proenkephalin 2.01232
OR2J3 olfactory receptor, family 2, subfamily J, member 3 2.01228
NUP58 nucleoporin 58 2.01211
PDLIM3 PDZ and LIM domain 3 2.01038
TRAPPC11 trafficking protein particle complex 11 2.00722
SPATA31A3 SPATA31 subfamily A, member 3 2.00688
CHN1 chimerin 1 2.00439
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 2.00437

decreased expression

Symbol Name Standardized Value
OXA1L oxidase (cytochrome c) assembly 1-like -5.20269
ETFB electron-transfer-flavoprotein, beta polypeptide -5.06651
ARFIP2 ADP-ribosylation factor interacting protein 2 -4.85521
AKT1 v-akt murine thymoma viral oncogene homolog 1 -4.71337
KIF14 kinesin family member 14 -4.64925
LDHD lactate dehydrogenase D -4.61866
DDIT4 DNA-damage-inducible transcript 4 -4.54666
TUBA4A tubulin, alpha 4a -4.4665
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -4.40078
KRT14 keratin 14, type I -4.30893
HSPB1 heat shock 27kDa protein 1 -4.27769
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -4.17662
TKT transketolase -4.14349
MT2A metallothionein 2A -4.10671
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.92428
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -3.89667
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -3.88345
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -3.868
FABP5 fatty acid binding protein 5 (psoriasis-associated) -3.84691
PLK1 polo-like kinase 1 -3.82454
TUFM Tu translation elongation factor, mitochondrial -3.74023
ILK integrin-linked kinase -3.67525
MVP major vault protein -3.66378
GFUS GDP-L-fucose synthase -3.63112
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -3.47641
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B -3.41293
DERA deoxyribose-phosphate aldolase (putative) -3.37823
HGS hepatocyte growth factor-regulated tyrosine kinase substrate -3.22145
ECH1 enoyl CoA hydratase 1, peroxisomal -3.20357
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 -3.18718
TFDP1 transcription factor Dp-1 -3.12199
DDB2 damage-specific DNA binding protein 2, 48kDa -3.05913
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -3.05781
TWF2 twinfilin actin binding protein 2 -3.0526
UQCRC1 ubiquinol-cytochrome c reductase core protein I -3.0265
ERCC2 excision repair cross-complementation group 2 -3.01833
UBE3C ubiquitin protein ligase E3C -2.9911
GYS1 glycogen synthase 1 (muscle) -2.98951
PFN1 profilin 1 -2.97789
GPS1 G protein pathway suppressor 1 -2.94753
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) -2.94248
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) -2.92974
CNN2 calponin 2 -2.92328
C1QBP complement component 1, q subcomponent binding protein -2.91285
NAP1L4 nucleosome assembly protein 1-like 4 -2.88296
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.87558
ANXA2 annexin A2 -2.87295
AXIN1 axin 1 -2.85589
UNC119 unc-119 homolog (C. elegans) -2.85587
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -2.84921
MRPS16 mitochondrial ribosomal protein S16 -2.84547
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 -2.74529
KIF2C kinesin family member 2C -2.73703
TP53 tumor protein p53 -2.7087
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -2.70238
LOC112694756 uncharaterized LOC112694756 -2.6923
MICALL1 MICAL-like 1 -2.68647
POLD4 polymerase (DNA-directed), delta 4, accessory subunit -2.6447
MRPL12 mitochondrial ribosomal protein L12 -2.63504
ETHE1 ethylmalonic encephalopathy 1 -2.6313
TNIP1 TNFAIP3 interacting protein 1 -2.61886
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -2.61516
PUF60 poly-U binding splicing factor 60KDa -2.58838
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 -2.58808
SPAG7 sperm associated antigen 7 -2.57094
TRIP6 thyroid hormone receptor interactor 6 -2.56293
MAPK3 mitogen-activated protein kinase 3 -2.54308
NT5DC2 5'-nucleotidase domain containing 2 -2.539
DUS1L dihydrouridine synthase 1-like (S. cerevisiae) -2.53497
IFRD2 interferon-related developmental regulator 2 -2.5303
WASF2 WAS protein family, member 2 -2.52904
CABIN1 calcineurin binding protein 1 -2.52805
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -2.51972
FPGS folylpolyglutamate synthase -2.5184
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -2.51071
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 -2.50128
ELAVL1 ELAV like RNA binding protein 1 -2.48975
INTS3 integrator complex subunit 3 -2.48588
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -2.48126
MARK4 MAP/microtubule affinity-regulating kinase 4 -2.4756
LASP1 LIM and SH3 protein 1 -2.46071
EPHB4 EPH receptor B4 -2.43503
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha -2.42813
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -2.41639
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.4075
EEIG1 estrogen-induced osteoclastogenesis regulator 1 -2.40678
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.40458
BAX BCL2-associated X protein -2.39379
PHB2 prohibitin 2 -2.38408
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -2.37118
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -2.36986
EIF4H eukaryotic translation initiation factor 4H -2.35488
TMEM115 transmembrane protein 115 -2.35401
TMEM214 transmembrane protein 214 -2.34882
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 -2.34685
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 -2.33729
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.335
CDK6 cyclin-dependent kinase 6 -2.33137
NT5C 5', 3'-nucleotidase, cytosolic -2.32368
TRIM28 tripartite motif containing 28 -2.31047
EPS8L2 EPS8-like 2 -2.30434
MT1X metallothionein 1X -2.29994
BID BH3 interacting domain death agonist -2.28671
CDCA4 cell division cycle associated 4 -2.28636
SCAP SREBF chaperone -2.2855
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -2.28386
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain -2.28176
SORBS3 sorbin and SH3 domain containing 3 -2.26886
CDC20 cell division cycle 20 -2.26825
ARMC6 armadillo repeat containing 6 -2.26296
ADGRE5 adhesion G protein-coupled receptor E5 -2.25992
RIC8A RIC8 guanine nucleotide exchange factor A -2.25581
ZYX zyxin -2.24847
RUVBL2 RuvB-like AAA ATPase 2 -2.24495
MTA1 metastasis associated 1 -2.23046
PTOV1 prostate tumor overexpressed 1 -2.2218
ARF5 ADP-ribosylation factor 5 -2.22153
PIEZO1 piezo-type mechanosensitive ion channel component 1 -2.21804
FLOT2 flotillin 2 -2.21582
COX5A cytochrome c oxidase subunit Va -2.20054
COX4I1 cytochrome c oxidase subunit IV isoform 1 -2.1966
AAAS achalasia, adrenocortical insufficiency, alacrimia -2.18929
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -2.18746
ZDHHC24 zinc finger, DHHC-type containing 24 -2.18598
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -2.18248
MPST mercaptopyruvate sulfurtransferase -2.1731
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -2.15852
CARM1 coactivator-associated arginine methyltransferase 1 -2.15469
BAG1 BCL2-associated athanogene -2.15259
ATP13A2 ATPase type 13A2 -2.14972
CTSZ cathepsin Z -2.1457
CSK c-src tyrosine kinase -2.14198
MRPL23 mitochondrial ribosomal protein L23 -2.1367
FDXR ferredoxin reductase -2.13468
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9 -2.12457
CARMIL1 capping protein regulator and myosin 1 linker 1 -2.12338
PLIN3 perilipin 3 -2.12313
STXBP2 syntaxin binding protein 2 -2.11751
CLUH clustered mitochondria (cluA/CLU1) homolog -2.1172
TPGS1 tubulin polyglutamylase complex subunit 1 -2.11656
EXOSC4 exosome component 4 -2.11602
POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3 -2.11254
AATF apoptosis antagonizing transcription factor -2.11192
FOXM1 forkhead box M1 -2.10534
ANKFY1 ankyrin repeat and FYVE domain containing 1 -2.10039
DPP3 dipeptidyl-peptidase 3 -2.09839
P4HB prolyl 4-hydroxylase, beta polypeptide -2.08743
CLIP2 CAP-GLY domain containing linker protein 2 -2.08485
GRWD1 glutamate-rich WD repeat containing 1 -2.07952
RAB17 RAB17, member RAS oncogene family -2.07708
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.07682
CDCA3 cell division cycle associated 3 -2.07667
AEN apoptosis enhancing nuclease -2.076
MALT1 MALT1 paracaspase -2.07059
C1RL complement component 1, r subcomponent-like -2.06872
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 -2.06577
ESRRA estrogen-related receptor alpha -2.06492
GATD3 glutamine amidotransferase class 1 domain containing 3 -2.06378
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -2.06037
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) -2.05872
EEF2 eukaryotic translation elongation factor 2 -2.05276
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 -2.04021
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -2.039
MAP2K2 mitogen-activated protein kinase kinase 2 -2.03877
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -2.0378
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -2.03767
PEBP1 phosphatidylethanolamine binding protein 1 -2.03654
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) -2.03649
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -2.02981
PGAM4 phosphoglycerate mutase family member 4 -2.02595
ERP29 endoplasmic reticulum protein 29 -2.02401
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -2.02061
ATP5F1B ATP synthase F1 subunit beta -2.02047
QARS1 glutaminyl-tRNA synthetase 1 -2.01445
GOLGA3 golgin A3 -2.01004
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) -2.00722
RALGDS ral guanine nucleotide dissociation stimulator -2.00394
ACTN1 actinin, alpha 1 -2.00283
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.00083