CRCGN016_MCF10A.TP53.M_24H:O17 Gene Set
Genes
47 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:O17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
5.28837
|
|
UBQLN2
|
ubiquilin 2
|
5.26136
|
|
SPAG4
|
sperm associated antigen 4
|
5.15877
|
|
KCTD5
|
potassium channel tetramerization domain containing 5
|
4.38385
|
|
KIF5C
|
kinesin family member 5C
|
4.14668
|
|
PTK2
|
protein tyrosine kinase 2
|
3.58539
|
|
TBPL1
|
TBP-like 1
|
3.44782
|
|
FZD7
|
frizzled class receptor 7
|
2.44652
|
|
ALDH1A3
|
aldehyde dehydrogenase 1 family, member A3
|
2.43581
|
|
SMARCC1
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
|
2.33733
|
|
FKBP14
|
FK506 binding protein 14, 22 kDa
|
2.31152
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.2583
|
|
PRR7
|
proline rich 7 (synaptic)
|
2.22242
|
|
RNF11
|
ring finger protein 11
|
2.18956
|
|
HAND1
|
heart and neural crest derivatives expressed 1
|
2.18268
|
|
NUP155
|
nucleoporin 155kDa
|
2.10889
|
|
MAB21L2
|
mab-21-like 2 (C. elegans)
|
2.10632
|
|
TMEM51
|
transmembrane protein 51
|
2.07803
|
|
DFFA
|
DNA fragmentation factor, 45kDa, alpha polypeptide
|
2.05792
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.04577
|
|
ABCC4
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
|
2.04415
|
|
DDHD2
|
DDHD domain containing 2
|
2.02397
|
|
ASB7
|
ankyrin repeat and SOCS box containing 7
|
2.00734
|
|
RIPPLY2-CYB5R4
|
RIPPLY2-CYB5R4 readthrough
|
2.0064
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
-5.86339
|
|
NLRP4
|
NLR family, pyrin domain containing 4
|
-5.25496
|
|
TIMP1
|
TIMP metallopeptidase inhibitor 1
|
-4.84767
|
|
GRN
|
granulin
|
-4.48511
|
|
ATF5
|
activating transcription factor 5
|
-4.34124
|
|
UFM1
|
ubiquitin-fold modifier 1
|
-3.90245
|
|
KRT14
|
keratin 14, type I
|
-3.51238
|
|
MSMO1
|
methylsterol monooxygenase 1
|
-2.90153
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-2.83824
|
|
MT1X
|
metallothionein 1X
|
-2.59957
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.5309
|
|
CYP4F3
|
cytochrome P450, family 4, subfamily F, polypeptide 3
|
-2.46194
|
|
EXT1
|
exostosin glycosyltransferase 1
|
-2.39684
|
|
STUB1
|
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
|
-2.33517
|
|
PSMB9
|
proteasome (prosome, macropain) subunit, beta type, 9
|
-2.2755
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-2.18194
|
|
CEBPA
|
CCAAT/enhancer binding protein (C/EBP), alpha
|
-2.14621
|
|
TUBA4A
|
tubulin, alpha 4a
|
-2.1351
|
|
VPS39
|
vacuolar protein sorting 39 homolog (S. cerevisiae)
|
-2.07466
|
|
ETFB
|
electron-transfer-flavoprotein, beta polypeptide
|
-2.07219
|
|
POLM
|
polymerase (DNA directed), mu
|
-2.07024
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.04908
|
|
SGK1
|
serum/glucocorticoid regulated kinase 1
|
-2.04737
|
