CRCGN016_MCF10A.TP53.M_24H:O19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tegafur 102.01 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

558 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:O19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
COMP cartilage oligomeric matrix protein 7.2002
E2F2 E2F transcription factor 2 4.30921
DCK deoxycytidine kinase 4.19712
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 4.1904
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.78437
PCNA proliferating cell nuclear antigen 3.67981
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 3.59166
PLSCR1 phospholipid scramblase 1 3.49599
CDC45 cell division cycle 45 3.40885
FZD7 frizzled class receptor 7 3.37888
ACAA1 acetyl-CoA acyltransferase 1 3.30455
CASP7 caspase 7, apoptosis-related cysteine peptidase 3.30118
PLAAT4 phospholipase A and acyltransferase 4 3.23822
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 3.20708
DSCC1 DNA replication and sister chromatid cohesion 1 3.1651
CADM1 cell adhesion molecule 1 3.08461
CHEK1 checkpoint kinase 1 3.0121
TCEA2 transcription elongation factor A (SII), 2 3.00153
FLCN folliculin 2.98212
CD69 CD69 molecule 2.92695
TGFB3 transforming growth factor, beta 3 2.84806
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 2.84188
HPGDS hematopoietic prostaglandin D synthase 2.84061
MFF mitochondrial fission factor 2.82995
ASPN asporin 2.82881
ADAM9 ADAM metallopeptidase domain 9 2.81748
MPC2 mitochondrial pyruvate carrier 2 2.8075
ARPP21 cAMP-regulated phosphoprotein, 21kDa 2.80447
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 2.78022
NMRK1 nicotinamide riboside kinase 1 2.77703
GRM2 glutamate receptor, metabotropic 2 2.77659
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.75622
CD2 CD2 molecule 2.74715
BET1 Bet1 golgi vesicular membrane trafficking protein 2.74573
MSRA methionine sulfoxide reductase A 2.73022
NEUROD6 neuronal differentiation 6 2.70265
GCH1 GTP cyclohydrolase 1 2.67346
MINPP1 multiple inositol-polyphosphate phosphatase 1 2.65147
CD247 CD247 molecule 2.64936
SATB1 SATB homeobox 1 2.64178
CD244 CD244 molecule, natural killer cell receptor 2B4 2.63643
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 2.6208
LGMN legumain 2.60058
GHR growth hormone receptor 2.59991
PARM1 prostate androgen-regulated mucin-like protein 1 2.59991
CRYZ crystallin, zeta (quinone reductase) 2.59019
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 2.58514
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 2.58439
SLC30A4 solute carrier family 30 (zinc transporter), member 4 2.57653
CISD1 CDGSH iron sulfur domain 1 2.56684
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 2.56678
SLC31A1 solute carrier family 31 (copper transporter), member 1 2.55023
CD101 CD101 molecule 2.54133
PROS1 protein S (alpha) 2.53427
TSPAN6 tetraspanin 6 2.53194
DNAI7 dynein axonemal intermediate chain 7 2.52645
PXDNL peroxidasin-like 2.51635
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 2.51516
TSPAN2 tetraspanin 2 2.51409
SPEF1 sperm flagellar 1 2.50129
C5 complement component 5 2.5001
GSAP gamma-secretase activating protein 2.49369
CA7 carbonic anhydrase VII 2.49238
LOC102724652 alpha-crystallin A chain 2.48775
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 2.47834
GUCA2B guanylate cyclase activator 2B (uroguanylin) 2.47685
FAM124B family with sequence similarity 124B 2.4741
RYR2 ryanodine receptor 2 (cardiac) 2.46955
BIN2 bridging integrator 2 2.46954
KLHL2 kelch-like family member 2 2.46782
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 2.4672
RAB17 RAB17, member RAS oncogene family 2.46546
LY6G5C lymphocyte antigen 6 complex, locus G5C 2.46013
MAGT1 magnesium transporter 1 2.45989
PDE1B phosphodiesterase 1B, calmodulin-dependent 2.45925
ADRB1 adrenoceptor beta 1 2.4425
HAT1 histone acetyltransferase 1 2.43936
UBA3 ubiquitin-like modifier activating enzyme 3 2.42884
N4BP2L1 NEDD4 binding protein 2-like 1 2.42758
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 2.42633
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 2.41956
STK38L serine/threonine kinase 38 like 2.41688
CA5B carbonic anhydrase VB, mitochondrial 2.41371
LRRC40 leucine rich repeat containing 40 2.41318
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 2.41167
TCP10L t-complex 10-like 2.40696
KL klotho 2.40693
LDOC1 leucine zipper, down-regulated in cancer 1 2.39944
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.39914
CCNA1 cyclin A1 2.39861
BCL2L14 BCL2-like 14 (apoptosis facilitator) 2.39841
NEIL1 nei endonuclease VIII-like 1 (E. coli) 2.39825
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 2.39786
TESPA1 thymocyte expressed, positive selection associated 1 2.39749
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 2.3848
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 2.38357
VAX2 ventral anterior homeobox 2 2.38029
SHOX short stature homeobox 2.37817
TSGA10 testis specific, 10 2.37609
POU3F4 POU class 3 homeobox 4 2.3704
WFDC2 WAP four-disulfide core domain 2 2.37028
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.36691
MAIP1 matrix AAA peptidase interacting protein 1 2.35914
SCN2B sodium channel, voltage gated, type II beta subunit 2.34846
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled 2.34307
CD48 CD48 molecule 2.34245
ANXA4 annexin A4 2.34007
TF transferrin 2.33871
MICB MHC class I polypeptide-related sequence B 2.33133
ADCY10 adenylate cyclase 10 (soluble) 2.3209
FBXO21 F-box protein 21 2.31951
STYK1 serine/threonine/tyrosine kinase 1 2.31475
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) 2.31168
DGKI diacylglycerol kinase, iota 2.31053
BTG4 B-cell translocation gene 4 2.30974
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 2.3097
TPO thyroid peroxidase 2.30947
POM121L2 POM121 transmembrane nucleoporin-like 2 2.30884
RRAGD Ras-related GTP binding D 2.30484
MCUB mitochondrial calcium uniporter dominant negative subunit beta 2.30452
RBMY1J RNA binding motif protein, Y-linked, family 1, member J 2.29916
LGALS12 lectin, galactoside-binding, soluble, 12 2.29838
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 2.29428
SCN9A sodium channel, voltage gated, type IX alpha subunit 2.2923
RPE65 retinal pigment epithelium-specific protein 65kDa 2.29226
SUMO1 small ubiquitin-like modifier 1 2.29138
SLC22A14 solute carrier family 22, member 14 2.28977
PRH1-TAS2R14 PRH1-TAS2R14 readthrough 2.28941
GFRA4 GDNF family receptor alpha 4 2.28508
DLX6 distal-less homeobox 6 2.28099
LOC122526780 uncharacterized LOC122526780 2.28086
ERLIN2 ER lipid raft associated 2 2.27724
JHY junctional cadherin complex regulator 2.27496
CXCR6 chemokine (C-X-C motif) receptor 6 2.27471
FMO3 flavin containing monooxygenase 3 2.27429
CTBS chitobiase, di-N-acetyl- 2.2727
DRD1 dopamine receptor D1 2.27234
RAD51AP1 RAD51 associated protein 1 2.269
TNMD tenomodulin 2.26732
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 2.2661
ISOC1 isochorismatase domain containing 1 2.26503
ASB9 ankyrin repeat and SOCS box containing 9 2.26279
EFHD1 EF-hand domain family, member D1 2.26183
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 2.26132
LRRC15 leucine rich repeat containing 15 2.26049
EYA3 EYA transcriptional coactivator and phosphatase 3 2.26039
DNAI4 dynein axonemal intermediate chain 4 2.26033
CD160 CD160 molecule 2.25861
MRPL44 mitochondrial ribosomal protein L44 2.25859
BMP15 bone morphogenetic protein 15 2.25842
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 2.2556
SPACA1 sperm acrosome associated 1 2.25414
BCAS2 breast carcinoma amplified sequence 2 2.25131
MYO3A myosin IIIA 2.25109
AP3M2 adaptor-related protein complex 3, mu 2 subunit 2.25038
DMRT1 doublesex and mab-3 related transcription factor 1 2.24732
LAIR2 leukocyte-associated immunoglobulin-like receptor 2 2.24596
STAB2 stabilin 2 2.2432
ZSCAN16 zinc finger and SCAN domain containing 16 2.23926
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 2.23745
AMELY amelogenin, Y-linked 2.2358
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 2.23158
SP140L SP140 nuclear body protein-like 2.22758
TPST2 tyrosylprotein sulfotransferase 2 2.22741
MPPED2 metallophosphoesterase domain containing 2 2.22636
IZUMO4 IZUMO family member 4 2.22482
LMO7 LIM domain 7 2.22119
FRMPD4 FERM and PDZ domain containing 4 2.22034
CCT8L2 chaperonin containing TCP1, subunit 8 (theta)-like 2 2.22017
KANSL1 KAT8 regulatory NSL complex subunit 1 2.2197
AQP8 aquaporin 8 2.21801
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 2.21717
BCL2A1 BCL2-related protein A1 2.21509
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 2.21374
B3GAT1 beta-1,3-glucuronyltransferase 1 2.21168
ZNF280B zinc finger protein 280B 2.20874
H2BC15 H2B clustered histone 15 2.20641
CMKLR1 chemerin chemokine-like receptor 1 2.20447
DAZL deleted in azoospermia-like 2.20428
ACAD8 acyl-CoA dehydrogenase family, member 8 2.20357
KRT83 keratin 83, type II 2.20323
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 2.20217
UBE2L6 ubiquitin-conjugating enzyme E2L 6 2.20082
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 2.19534
FBXW10B F-box and WD repeat domain containing 10B 2.19448
UBASH3A ubiquitin associated and SH3 domain containing A 2.19433
GPC4 glypican 4 2.1923
HID1 HID1 domain containing 2.19221
MORC4 MORC family CW-type zinc finger 4 2.19187
AKAP4 A kinase (PRKA) anchor protein 4 2.19155
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 2.1905
RAX retina and anterior neural fold homeobox 2.18839
APOL1 apolipoprotein L, 1 2.18675
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 2.18643
CLEC7A C-type lectin domain family 7, member A 2.18616
TLR3 toll-like receptor 3 2.18401
RAP2C RAP2C, member of RAS oncogene family 2.18343
CLUL1 clusterin-like 1 (retinal) 2.18054
BRDT bromodomain, testis-specific 2.17949
PLSCR2 phospholipid scramblase 2 2.17818
HTN1 histatin 1 2.1768
COL8A2 collagen, type VIII, alpha 2 2.17501
OCM2 oncomodulin 2 2.17476
DNAH6 dynein, axonemal, heavy chain 6 2.17284
CCL5 chemokine (C-C motif) ligand 5 2.17103
FGF7 fibroblast growth factor 7 2.16365
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 2.16101
GZMM granzyme M (lymphocyte met-ase 1) 2.16084
STXBP3 syntaxin binding protein 3 2.1601
AMT aminomethyltransferase 2.15788
SOX14 SRY (sex determining region Y)-box 14 2.15536
SIDT1 SID1 transmembrane family, member 1 2.15466
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 2.15391
GNG13 guanine nucleotide binding protein (G protein), gamma 13 2.15281
RECQL RecQ helicase-like 2.15248
TXNDC9 thioredoxin domain containing 9 2.15226
AQP7 aquaporin 7 2.15102
GET1 guided entry of tail-anchored proteins factor 1 2.1476
TEX13A testis expressed 13A 2.14614
HLA-DMA major histocompatibility complex, class II, DM alpha 2.14595
SPATA31A3 SPATA31 subfamily A, member 3 2.1438
FN3K fructosamine 3 kinase 2.14074
ZNF639 zinc finger protein 639 2.14021
TSBP1 testis expressed basic protein 1 2.13693
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 2.1366
RFK riboflavin kinase 2.13606
PTGDR2 prostaglandin D2 receptor 2 2.13439
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 2.13254
TMEM106B transmembrane protein 106B 2.13093
CGRRF1 cell growth regulator with ring finger domain 1 2.12924
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 2.1289
MYBPH myosin binding protein H 2.1279
NXPE4 neurexophilin and PC-esterase domain family, member 4 2.12599
KISS1 KiSS-1 metastasis-suppressor 2.12317
OR7A5 olfactory receptor, family 7, subfamily A, member 5 2.12071
SCN5A sodium channel, voltage gated, type V alpha subunit 2.12047
GNLY granulysin 2.12022
AURKC aurora kinase C 2.11911
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K 2.11865
SH3GL3 SH3-domain GRB2-like 3 2.11861
SAA4 serum amyloid A4, constitutive 2.11849
NOX4 NADPH oxidase 4 2.11805
AKAP5 A kinase (PRKA) anchor protein 5 2.11757
DDR1 discoidin domain receptor tyrosine kinase 1 2.11734
CNKSR2 connector enhancer of kinase suppressor of Ras 2 2.11722
TMEM35B transmembrane protein 35B 2.11549
PSMC3IP PSMC3 interacting protein 2.11533
TXK TXK tyrosine kinase 2.11355
TOPBP1 topoisomerase (DNA) II binding protein 1 2.11315
KRT33B keratin 33B, type I 2.11314
ACKR5 atypical chemokine receptor 5 2.112
ADGRE5 adhesion G protein-coupled receptor E5 2.11044
FGF9 fibroblast growth factor 9 2.10977
ZNF85 zinc finger protein 85 2.10712
GPR85 G protein-coupled receptor 85 2.10691
NKX3-1 NK3 homeobox 1 2.10643
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 2.10623
ZDHHC13 zinc finger, DHHC-type containing 13 2.10286
PLS3 plastin 3 2.10275
PYHIN1 pyrin and HIN domain family, member 1 2.1019
TRIM49D2 tripartite motif containing 49D2 2.09978
SMR3A submaxillary gland androgen regulated protein 3A 2.09903
ZNF529 zinc finger protein 529 2.09094
FAM90A1 family with sequence similarity 90, member A1 2.09035
GTPBP8 GTP-binding protein 8 (putative) 2.08951
TSPOAP1 TSPO associated protein 1 2.08908
RLN1 relaxin 1 2.08854
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 2.08657
ANKRD37 ankyrin repeat domain 37 2.08614
SMR3B submaxillary gland androgen regulated protein 3B 2.08557
DRP2 dystrophin related protein 2 2.08433
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8 2.08376
TTC9 tetratricopeptide repeat domain 9 2.08162
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 2.07867
ARMCX2 armadillo repeat containing, X-linked 2 2.0771
NUAK1 NUAK family, SNF1-like kinase, 1 2.07533
EPPIN epididymal peptidase inhibitor 2.07439
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 2.07419
COL14A1 collagen, type XIV, alpha 1 2.07344
EFR3B EFR3 homolog B (S. cerevisiae) 2.07249
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 2.07219
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 2.07044
RIT2 Ras-like without CAAX 2 2.06999
CHRM5 cholinergic receptor, muscarinic 5 2.06854
TEX15 testis expressed 15 2.06755
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 2.06679
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 2.0667
LSP1 lymphocyte-specific protein 1 2.0655
CYB5R1 cytochrome b5 reductase 1 2.06328
YEATS4 YEATS domain containing 4 2.06166
LMTK2 lemur tyrosine kinase 2 2.06143
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 2.06054
TMEM14B transmembrane protein 14B 2.0601
PGK2 phosphoglycerate kinase 2 2.0598
LIFR leukemia inhibitory factor receptor alpha 2.05736
OR3A2 olfactory receptor, family 3, subfamily A, member 2 2.05453
HPCA hippocalcin 2.05392
CCNDBP1 cyclin D-type binding-protein 1 2.05067
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 2.05054
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 2.05036
ADGB androglobin 2.05029
PLAAT2 phospholipase A and acyltransferase 2 2.05023
POLI polymerase (DNA directed) iota 2.04902
STEEP1 STING1 ER exit protein 1 2.04755
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 2.04742
LOC124906741 sperm-associated antigen 11B-like 2.04738
TEX28 testis expressed 28 2.04712
PPP1R2C PPP1R2C family member C 2.04703
PSG4 pregnancy specific beta-1-glycoprotein 4 2.04612
GRK3 G protein-coupled receptor kinase 3 2.04576
ASGR2 asialoglycoprotein receptor 2 2.04545
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 2.04453
RERGL RERG/RAS-like 2.04406
AMOT angiomotin 2.04398
IDO1 indoleamine 2,3-dioxygenase 1 2.04371
EED embryonic ectoderm development 2.04167
PLCH1 phospholipase C, eta 1 2.04125
PLCB2 phospholipase C, beta 2 2.04096
RNF17 ring finger protein 17 2.04021
MYO1F myosin IF 2.03904
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 2.0387
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 2.03869
CPLX3 complexin 3 2.03748
CYRIB CYFIP related Rac1 interactor B 2.03713
TACR2 tachykinin receptor 2 2.03629
DEFB126 defensin, beta 126 2.03598
HPSE2 heparanase 2 (inactive) 2.03576
PSG2 pregnancy specific beta-1-glycoprotein 2 2.03567
HNRNPCL1 heterogeneous nuclear ribonucleoprotein C-like 1 2.03556
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 2.03535
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 2.03507
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 2.03383
VN1R1 vomeronasal 1 receptor 1 2.03315
SULF1 sulfatase 1 2.03299
SIX6 SIX homeobox 6 2.03289
SSX1 synovial sarcoma, X breakpoint 1 2.03173
CNGB3 cyclic nucleotide gated channel beta 3 2.02808
CRTAM cytotoxic and regulatory T cell molecule 2.0271
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 2.02698
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 2.02594
ELSPBP1 epididymal sperm binding protein 1 2.02511
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) 2.0251
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa 2.02484
AQP6 aquaporin 6, kidney specific 2.0233
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 2.02288
PEX13 peroxisomal biogenesis factor 13 2.01905
NIBAN1 niban apoptosis regulator 1 2.01885
GINS1 GINS complex subunit 1 (Psf1 homolog) 2.01877
PARD6B par-6 family cell polarity regulator beta 2.01859
ADRA1A adrenoceptor alpha 1A 2.01822
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) 2.01735
POLD3 polymerase (DNA-directed), delta 3, accessory subunit 2.01558
SGPP2 sphingosine-1-phosphate phosphatase 2 2.01506
HMHB1 histocompatibility (minor) HB-1 2.01466
TEX13B testis expressed 13B 2.01159
GPR21 G protein-coupled receptor 21 2.01149
LUZP4 leucine zipper protein 4 2.0113
GTPBP10 GTP-binding protein 10 (putative) 2.00991
JCHAIN joining chain of multimeric IgA and IgM 2.00989
CELF2 CUGBP, Elav-like family member 2 2.00774
MAGIX MAGI family member, X-linked 2.00692
PDGFRL platelet-derived growth factor receptor-like 2.00574
PCDHA2 protocadherin alpha 2 2.00476
PAH phenylalanine hydroxylase 2.0035
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) 2.00137
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 2.00021
MYOM2 myomesin 2 2.00011

decreased expression

Symbol Name Standardized Value
KIF20A kinesin family member 20A -8.00791
PLK1 polo-like kinase 1 -7.8513
UBE2C ubiquitin-conjugating enzyme E2C -7.69191
CDC20 cell division cycle 20 -7.51568
KRT14 keratin 14, type I -6.2862
BASP1 brain abundant, membrane attached signal protein 1 -5.4801
TOP2A topoisomerase (DNA) II alpha 170kDa -4.89463
GRWD1 glutamate-rich WD repeat containing 1 -4.82954
CASC3 cancer susceptibility candidate 3 -4.79225
NUP85 nucleoporin 85kDa -4.61757
KIF14 kinesin family member 14 -4.54103
CDC25B cell division cycle 25B -4.51462
CCNB2 cyclin B2 -4.37834
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -4.30639
PSRC1 proline/serine-rich coiled-coil 1 -4.23593
DDIT4 DNA-damage-inducible transcript 4 -3.81734
TUFM Tu translation elongation factor, mitochondrial -3.81168
NUSAP1 nucleolar and spindle associated protein 1 -3.77462
WASF2 WAS protein family, member 2 -3.66714
MRPS2 mitochondrial ribosomal protein S2 -3.60238
KIF4A kinesin family member 4A -3.54531
SAP30BP SAP30 binding protein -3.40271
CLTB clathrin, light chain B -3.3888
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.29919
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 -3.29038
JPT1 Jupiter microtubule associated homolog 1 -3.28337
HMMR hyaluronan-mediated motility receptor (RHAMM) -3.25288
PUF60 poly-U binding splicing factor 60KDa -3.24949
PRC1 protein regulator of cytokinesis 1 -3.23127
BIRC5 baculoviral IAP repeat containing 5 -3.22924
ANXA2 annexin A2 -3.20935
MRPS7 mitochondrial ribosomal protein S7 -3.20486
CCNB1 cyclin B1 -3.18783
MED24 mediator complex subunit 24 -3.16838
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -3.16141
TPX2 TPX2, microtubule-associated -3.07962
MRPL58 mitochondrial ribosomal protein L58 -3.05103
UBE2S ubiquitin-conjugating enzyme E2S -3.0146
AKT1 v-akt murine thymoma viral oncogene homolog 1 -2.98365
NAT9 N-acetyltransferase 9 (GCN5-related, putative) -2.94419
GFUS GDP-L-fucose synthase -2.90649
TNIP1 TNFAIP3 interacting protein 1 -2.89591
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.88864
EIF3CL eukaryotic translation initiation factor 3, subunit C-like -2.87504
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.85915
MRPL24 mitochondrial ribosomal protein L24 -2.84894
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -2.8249
DTD1 D-tyrosyl-tRNA deacylase 1 -2.814
KCTD2 potassium channel tetramerization domain containing 2 -2.80959
NHP2 NHP2 ribonucleoprotein -2.80081
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -2.79691
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -2.79025
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) -2.77488
TKT transketolase -2.7722
PCCB propionyl CoA carboxylase, beta polypeptide -2.76351
FPGS folylpolyglutamate synthase -2.75995
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.74956
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) -2.73368
MGLL monoglyceride lipase -2.7095
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) -2.69612
MRPL12 mitochondrial ribosomal protein L12 -2.69579
ECH1 enoyl CoA hydratase 1, peroxisomal -2.65473
NCAPD2 non-SMC condensin I complex, subunit D2 -2.6402
MT1X metallothionein 1X -2.63563
ATP5PD ATP synthase peripheral stalk subunit d -2.6229
KLC1 kinesin light chain 1 -2.62196
CENPA centromere protein A -2.60628
TACC3 transforming, acidic coiled-coil containing protein 3 -2.59125
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.58394
MYC v-myc avian myelocytomatosis viral oncogene homolog -2.57307
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.56899
RBM10 RNA binding motif protein 10 -2.56504
NOP16 NOP16 nucleolar protein -2.56494
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 -2.56056
PTTG1 pituitary tumor-transforming 1 -2.55456
AURKA aurora kinase A -2.5434
CD81 CD81 molecule -2.53771
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.53644
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.53573
DCTN4 dynactin 4 (p62) -2.51461
PCBP1 poly(rC) binding protein 1 -2.50283
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -2.48689
TRIM28 tripartite motif containing 28 -2.48374
COTL1 coactosin-like F-actin binding protein 1 -2.48181
MT2A metallothionein 2A -2.47885
CCT7 chaperonin containing TCP1, subunit 7 (eta) -2.47459
TUBA4A tubulin, alpha 4a -2.46599
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 -2.46447
OXA1L oxidase (cytochrome c) assembly 1-like -2.44429
GPSM2 G-protein signaling modulator 2 -2.44335
LARP1 La ribonucleoprotein domain family, member 1 -2.43409
TM9SF3 transmembrane 9 superfamily member 3 -2.4197
PTOV1 prostate tumor overexpressed 1 -2.40451
ETFB electron-transfer-flavoprotein, beta polypeptide -2.40107
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.39192
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 -2.3903
AP2M1 adaptor-related protein complex 2, mu 1 subunit -2.37587
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -2.37577
TUBB6 tubulin, beta 6 class V -2.37132
LASP1 LIM and SH3 protein 1 -2.36938
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 -2.36444
CDCA3 cell division cycle associated 3 -2.3617
YY1AP1 YY1 associated protein 1 -2.36113
SSR2 signal sequence receptor, beta (translocon-associated protein beta) -2.35911
RBM6 RNA binding motif protein 6 -2.35791
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 -2.35557
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) -2.35178
HARS1 histidyl-tRNA synthetase 1 -2.34997
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -2.34781
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha -2.33304
STOML2 stomatin (EPB72)-like 2 -2.32565
TIMP1 TIMP metallopeptidase inhibitor 1 -2.32039
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -2.32035
SCARB1 scavenger receptor class B, member 1 -2.30622
MAT2A methionine adenosyltransferase II, alpha -2.2948
ACOT7 acyl-CoA thioesterase 7 -2.28846
AAR2 AAR2 splicing factor homolog (S. cerevisiae) -2.28474
HDAC3 histone deacetylase 3 -2.28257
BMS1 BMS1 ribosome biogenesis factor -2.25776
CDCA8 cell division cycle associated 8 -2.25272
RNF40 ring finger protein 40, E3 ubiquitin protein ligase -2.24385
CDKN3 cyclin-dependent kinase inhibitor 3 -2.24102
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.23392
CSK c-src tyrosine kinase -2.23302
AATF apoptosis antagonizing transcription factor -2.23126
IRAK1 interleukin-1 receptor-associated kinase 1 -2.22993
MSL1 male-specific lethal 1 homolog (Drosophila) -2.22719
LPIN1 lipin 1 -2.21974
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -2.21961
UQCRC1 ubiquinol-cytochrome c reductase core protein I -2.21873
GRB2 growth factor receptor-bound protein 2 -2.21602
NOLC1 nucleolar and coiled-body phosphoprotein 1 -2.21424
KIF2C kinesin family member 2C -2.20458
SETD5 SET domain containing 5 -2.20446
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.20345
MTX1 metaxin 1 -2.20199
RUVBL1 RuvB-like AAA ATPase 1 -2.20055
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -2.19878
H3-3B H3.3 histone B -2.18284
TFDP1 transcription factor Dp-1 -2.18208
XPO6 exportin 6 -2.17933
FKBP5 FK506 binding protein 5 -2.17176
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -2.164
TWF2 twinfilin actin binding protein 2 -2.15903
FOXM1 forkhead box M1 -2.15718
SMTN smoothelin -2.15504
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) -2.15484
APRT adenine phosphoribosyltransferase -2.15392
MKI67 marker of proliferation Ki-67 -2.15076
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -2.1482
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -2.14624
FBL fibrillarin -2.13845
RBMX RNA binding motif protein, X-linked -2.13684
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.13292
CKAP5 cytoskeleton associated protein 5 -2.12821
ATP5F1B ATP synthase F1 subunit beta -2.12305
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -2.11829
RCOR1 REST corepressor 1 -2.1168
RPAP1 RNA polymerase II associated protein 1 -2.11366
HEATR1 HEAT repeat containing 1 -2.11324
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.11127
ZYX zyxin -2.10289
CAB39 calcium binding protein 39 -2.1002
MOGAT1 monoacylglycerol O-acyltransferase 1 -2.0998
TLE3 transducin-like enhancer of split 3 -2.09972
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -2.09475
NCOA3 nuclear receptor coactivator 3 -2.08109
ATP5MC1 ATP synthase membrane subunit c locus 1 -2.08087
LDLR low density lipoprotein receptor -2.07412
MCL1 myeloid cell leukemia 1 -2.06881
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -2.05875
CENPE centromere protein E, 312kDa -2.05462
SRSF2 serine/arginine-rich splicing factor 2 -2.05445
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 -2.05372
GPS1 G protein pathway suppressor 1 -2.05329
EGLN2 egl-9 family hypoxia-inducible factor 2 -2.04692
ATP13A1 ATPase type 13A1 -2.04531
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -2.03924
CIRBP cold inducible RNA binding protein -2.03814
CDR2L cerebellar degeneration-related protein 2-like -2.02991
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.02905
TBC1D10B TBC1 domain family, member 10B -2.02816
VCP valosin containing protein -2.02434
DEPDC1 DEP domain containing 1 -2.02056
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) -2.01566
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -2.01433
RBM23 RNA binding motif protein 23 -2.01374
SUN2 Sad1 and UNC84 domain containing 2 -2.01078
IST1 increased sodium tolerance 1 homolog (yeast) -2.01059
INTS3 integrator complex subunit 3 -2.00298
SNF8 SNF8, ESCRT-II complex subunit -2.00256