CRCGN016_MCF10A.TP53.M_24H:P04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benz(a)anthracene 100.17 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

38 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:P04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 5.551
ZNF586 zinc finger protein 586 4.5061
FGFR4 fibroblast growth factor receptor 4 4.27052
MICALL1 MICAL-like 1 3.98165
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.34155
ZNF134 zinc finger protein 134 3.3156
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.88305
ZNF419 zinc finger protein 419 2.67225
ZNF211 zinc finger protein 211 2.559
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.55215
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.53022
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 2.46242
ZIM3 zinc finger, imprinted 3 2.3093
ZNF551 zinc finger protein 551 2.2481
ZNF329 zinc finger protein 329 2.2452
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.17325
MCMBP minichromosome maintenance complex binding protein 2.1525
GPX7 glutathione peroxidase 7 2.14935
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.11885
TRIM32 tripartite motif containing 32 2.1112
NAMPT nicotinamide phosphoribosyltransferase 2.09262
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.05395
CCR7 chemokine (C-C motif) receptor 7 2.04005
PRKCD protein kinase C, delta 2.0166
CAB39 calcium binding protein 39 2.01605

decreased expression

Symbol Name Standardized Value
CHMP4B charged multivesicular body protein 4B -5.42828
PCCB propionyl CoA carboxylase, beta polypeptide -5.2246
RNF167 ring finger protein 167 -5.0346
UFM1 ubiquitin-fold modifier 1 -4.62025
PSIP1 PC4 and SFRS1 interacting protein 1 -3.1889
MACF1 microtubule-actin crosslinking factor 1 -2.3157
BEX2 brain expressed X-linked 2 -2.1621
MSN moesin -2.14015
PIH1D1 PIH1 domain containing 1 -2.12705
SPAG4 sperm associated antigen 4 -2.07225
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 -2.03425
ZNF205 zinc finger protein 205 -2.02265
NANOS2 nanos homolog 2 (Drosophila) -2.00435