CRCGN016_MCF10A.TP53.M_24H:P05 Gene Set
Genes
59 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:P05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LAGE3
|
L antigen family, member 3
|
4.78265
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
4.67905
|
|
SESN1
|
sestrin 1
|
4.5689
|
|
CCNA1
|
cyclin A1
|
3.93575
|
|
STAT3
|
signal transducer and activator of transcription 3 (acute-phase response factor)
|
3.8184
|
|
WIF1
|
WNT inhibitory factor 1
|
3.52705
|
|
TBPL1
|
TBP-like 1
|
3.18155
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
2.93025
|
|
COMP
|
cartilage oligomeric matrix protein
|
2.8747
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
2.72255
|
|
CADM1
|
cell adhesion molecule 1
|
2.57597
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
2.36497
|
|
UBL4A
|
ubiquitin-like 4A
|
2.3354
|
|
IL13RA2
|
interleukin 13 receptor, alpha 2
|
2.2324
|
|
SLC26A2
|
solute carrier family 26 (anion exchanger), member 2
|
2.2322
|
|
C1S
|
complement component 1, s subcomponent
|
2.222
|
|
SYNGAP1
|
synaptic Ras GTPase activating protein 1
|
2.18087
|
|
PCOLCE
|
procollagen C-endopeptidase enhancer
|
2.16185
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.1598
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.0956
|
|
SLC10A3
|
solute carrier family 10, member 3
|
2.0761
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.0722
|
|
TBCCD1
|
TBCC domain containing 1
|
2.06185
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.0015
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HMG20B
|
high mobility group 20B
|
-9.88558
|
|
NLRP4
|
NLR family, pyrin domain containing 4
|
-7.75325
|
|
YME1L1
|
YME1-like 1 ATPase
|
-5.16495
|
|
PLK1
|
polo-like kinase 1
|
-4.6984
|
|
TEX10
|
testis expressed 10
|
-4.65705
|
|
MPC2
|
mitochondrial pyruvate carrier 2
|
-4.55295
|
|
TCTA
|
T-cell leukemia translocation altered
|
-4.4103
|
|
WASHC4
|
WASH complex subunit 4
|
-4.39052
|
|
OXCT1
|
3-oxoacid CoA transferase 1
|
-4.298
|
|
TP53
|
tumor protein p53
|
-3.81428
|
|
CLN3
|
ceroid-lipofuscinosis, neuronal 3
|
-3.00167
|
|
BASP1
|
brain abundant, membrane attached signal protein 1
|
-2.983
|
|
MFSD12
|
major facilitator superfamily domain containing 12
|
-2.92222
|
|
THOP1
|
thimet oligopeptidase 1
|
-2.6451
|
|
RAD51C
|
RAD51 paralog C
|
-2.4579
|
|
HERC1
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
|
-2.43045
|
|
AAAS
|
achalasia, adrenocortical insufficiency, alacrimia
|
-2.3599
|
|
ABI1
|
abl-interactor 1
|
-2.32067
|
|
DXO
|
decapping exoribonuclease
|
-2.29597
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.23175
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
-2.2122
|
|
WAC
|
WW domain containing adaptor with coiled-coil
|
-2.19403
|
|
PDSS1
|
prenyl (decaprenyl) diphosphate synthase, subunit 1
|
-2.15585
|
|
SLC16A6
|
solute carrier family 16, member 6
|
-2.1433
|
|
ZNF248
|
zinc finger protein 248
|
-2.1202
|
|
CACTIN
|
cactin, spliceosome C complex subunit
|
-2.11222
|
|
CD81
|
CD81 molecule
|
-2.09735
|
|
SYNRG
|
synergin, gamma
|
-2.07765
|
|
CD24
|
CD24 molecule
|
-2.06269
|
|
UBXN6
|
UBX domain protein 6
|
-2.0421
|
|
MSMO1
|
methylsterol monooxygenase 1
|
-2.0363
|
|
RPAP1
|
RNA polymerase II associated protein 1
|
-2.03055
|
|
BANP
|
BTG3 associated nuclear protein
|
-2.0199
|
|
MAP2K2
|
mitogen-activated protein kinase kinase 2
|
-2.00857
|
|
KIF5B
|
kinesin family member 5B
|
-2.00155
|
