CRCGN016_MCF10A.TP53.M_24H:P06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benz(a)anthracene 11.13 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:P06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCNA1 cyclin A1 4.86285
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 3.81195
COMP cartilage oligomeric matrix protein 3.52655
RAB21 RAB21, member RAS oncogene family 3.34095
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.8708
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.4661
TXNL4B thioredoxin-like 4B 2.41
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.3411
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.23675
LYN LYN proto-oncogene, Src family tyrosine kinase 2.16453
HPGDS hematopoietic prostaglandin D synthase 2.0892
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.01245

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -5.20683
HACD3 3-hydroxyacyl-CoA dehydratase 3 -5.20195
DSG2 desmoglein 2 -4.9785
ATF5 activating transcription factor 5 -4.74718
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -4.62747
KRT14 keratin 14, type I -3.28815
GRN granulin -2.90465
CRTAP cartilage associated protein -2.4134
CAPN2 calpain 2, (m/II) large subunit -2.121
MPC2 mitochondrial pyruvate carrier 2 -2.10455