CRCGN016_MCF10A.TP53.M_24H:P15 Gene Set
Genes
50 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:P15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.865
|
|
PRKX
|
protein kinase, X-linked
|
4.6905
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
4.3546
|
|
SPAG4
|
sperm associated antigen 4
|
4.25675
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
3.4084
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.92985
|
|
HBA1
|
hemoglobin, alpha 1
|
2.81306
|
|
PXMP2
|
peroxisomal membrane protein 2, 22kDa
|
2.77787
|
|
RFX5
|
regulatory factor X, 5 (influences HLA class II expression)
|
2.49385
|
|
BMAL1
|
basic helix-loop-helix ARNT like 1
|
2.47258
|
|
VAPB
|
VAMP (vesicle-associated membrane protein)-associated protein B and C
|
2.3236
|
|
FZD4
|
frizzled class receptor 4
|
2.282
|
|
PCNP
|
PEST proteolytic signal containing nuclear protein
|
2.21435
|
|
CCNA1
|
cyclin A1
|
2.1956
|
|
HTR3A
|
5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
|
2.1513
|
|
COQ8A
|
coenzyme Q8A
|
2.1312
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.12585
|
|
HEBP2
|
heme binding protein 2
|
2.118
|
|
SELENOF
|
selenoprotein F
|
2.11025
|
|
TERF2
|
telomeric repeat binding factor 2
|
2.1097
|
|
RABL3
|
RAB, member of RAS oncogene family-like 3
|
2.1028
|
|
RLIG1
|
RNA 5'-phosphate and 3'-OH ligase 1
|
2.06005
|
|
DLST
|
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
|
2.04785
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-5.16505
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-5.10625
|
|
KRT14
|
keratin 14, type I
|
-4.3643
|
|
S100A8
|
S100 calcium binding protein A8
|
-4.311
|
|
PFN1
|
profilin 1
|
-4.01895
|
|
SQSTM1
|
sequestosome 1
|
-3.5307
|
|
EPHX1
|
epoxide hydrolase 1, microsomal (xenobiotic)
|
-3.2241
|
|
KIF20A
|
kinesin family member 20A
|
-3.1691
|
|
IPO13
|
importin 13
|
-3.07715
|
|
REXO2
|
RNA exonuclease 2
|
-2.87759
|
|
HIF1A
|
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
|
-2.7119
|
|
TRAP1
|
TNF receptor-associated protein 1
|
-2.6091
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.5104
|
|
BASP1
|
brain abundant, membrane attached signal protein 1
|
-2.46985
|
|
SH3BP1
|
SH3-domain binding protein 1
|
-2.42025
|
|
PARP8
|
poly (ADP-ribose) polymerase family, member 8
|
-2.21175
|
|
DAAM2
|
dishevelled associated activator of morphogenesis 2
|
-2.2098
|
|
SLC38A10
|
solute carrier family 38, member 10
|
-2.1828
|
|
TUBA4A
|
tubulin, alpha 4a
|
-2.16215
|
|
GOLGA8N
|
golgin A8 family, member N
|
-2.1509
|
|
TNFSF9
|
tumor necrosis factor (ligand) superfamily, member 9
|
-2.14315
|
|
PLOD3
|
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
|
-2.14245
|
|
VWA1
|
von Willebrand factor A domain containing 1
|
-2.13445
|
|
RUNX3
|
runt-related transcription factor 3
|
-2.06932
|
|
SF3B4
|
splicing factor 3b, subunit 4, 49kDa
|
-2.0151
|
|
QSOX1
|
quiescin Q6 sulfhydryl oxidase 1
|
-2.0014
|
|
PHC1
|
polyhomeotic homolog 1 (Drosophila)
|
-2.00115
|
